BRENDA - Enzyme Database show

Component requirements for NADH inhibition and spermine stimulation of pyruvate dehydrogenase phosphatase activity

Rahmatullah, M.; Roche, T.E.; J. Biol. Chem. 263, 8106-8110 (1988)

Data extracted from this reference:

Activating Compound
EC Number
Activating Compound
Commentary
Organism
Structure
3.1.3.43
spermine
-
Bos taurus
Inhibitors
EC Number
Inhibitors
Commentary
Organism
Structure
3.1.3.43
arsenite
together with NADH
Bos taurus
3.1.3.43
dihydrolipoamide
-
Bos taurus
3.1.3.43
NADH
-
Bos taurus
Metals/Ions
EC Number
Metals/Ions
Commentary
Organism
Structure
3.1.3.43
Ca2+
-
Bos taurus
Natural Substrates/ Products (Substrates)
EC Number
Natural Substrates
Organism
Commentary (Nat. Sub.)
Natural Products
Commentary (Nat. Pro.)
Organism (Nat. Pro.)
Reversibility
3.1.3.43
[pyruvate dehydrogenase (lipoamide)]-phosphate + H2O
Bos taurus
-
?
-
-
-
Organism
EC Number
Organism
Primary Accession No. (UniProt)
Commentary
Textmining
3.1.3.43
Bos taurus
-
-
-
Source Tissue
EC Number
Source Tissue
Commentary
Organism
Textmining
3.1.3.43
heart
-
Bos taurus
-
3.1.3.43
kidney
-
Bos taurus
-
Substrates and Products (Substrate)
EC Number
Substrates
Commentary Substrates
Literature (Substrates)
Organism
Products
Commentary (Products)
Literature (Products)
Organism (Products)
Reversibility
3.1.3.43
[pyruvate dehydrogenase (lipoamide)]-phosphate + H2O
-
94880
Bos taurus
[pyruvate dehydrogenase (lipoamide)] + phosphate
-
94880
Bos taurus
ir
3.1.3.43
[pyruvate dehydrogenase (lipoamide)]-phosphate + H2O
-
94880
Bos taurus
?
-
-
-
-
Activating Compound (protein specific)
EC Number
Activating Compound
Commentary
Organism
Structure
3.1.3.43
spermine
-
Bos taurus
Inhibitors (protein specific)
EC Number
Inhibitors
Commentary
Organism
Structure
3.1.3.43
arsenite
together with NADH
Bos taurus
3.1.3.43
dihydrolipoamide
-
Bos taurus
3.1.3.43
NADH
-
Bos taurus
Metals/Ions (protein specific)
EC Number
Metals/Ions
Commentary
Organism
Structure
3.1.3.43
Ca2+
-
Bos taurus
Natural Substrates/ Products (Substrates) (protein specific)
EC Number
Natural Substrates
Organism
Commentary (Nat. Sub.)
Natural Products
Commentary (Nat. Pro.)
Organism (Nat. Pro.)
Reversibility
3.1.3.43
[pyruvate dehydrogenase (lipoamide)]-phosphate + H2O
Bos taurus
-
?
-
-
-
Source Tissue (protein specific)
EC Number
Source Tissue
Commentary
Organism
Textmining
3.1.3.43
heart
-
Bos taurus
-
3.1.3.43
kidney
-
Bos taurus
-
Substrates and Products (Substrate) (protein specific)
EC Number
Substrates
Commentary Substrates
Literature (Substrates)
Organism
Products
Commentary (Products)
Literature (Products)
Organism (Products)
Reversibility
3.1.3.43
[pyruvate dehydrogenase (lipoamide)]-phosphate + H2O
-
94880
Bos taurus
[pyruvate dehydrogenase (lipoamide)] + phosphate
-
94880
Bos taurus
ir
3.1.3.43
[pyruvate dehydrogenase (lipoamide)]-phosphate + H2O
-
94880
Bos taurus
?
-
-
-
-