Any feedback?
Literature summary extracted from
- Properties of amphiphilic and hydrophilic forms of alkaline phosphatase from human liver (1991), Enzyme, 45, 155-164.
Activating Compound
| EC Number | Activating Compound | Comment | Organism | Structure |
|---|---|---|---|---|
| 3.1.3.1 | albumin | 3fold stimulation of hydrophilic enzyme, slight stimulation of amphiphilic enzyme | Homo sapiens | |
| 3.1.3.1 | phosphatidylcholine | 1fold stimulation of hydrophilic enzyme form | Homo sapiens |  |
| 3.1.3.1 | phosphatidylethanolamine | 1fold stimulation of hydrophilic enzyme form | Homo sapiens | |
| 3.1.3.1 | phosphatidylinositol | 1.5fold stimulation of hydrophilic enzyme form | Homo sapiens | |
| 3.1.3.1 | phosphatidylserine | 1fold stimulation of amphiphilic enzyme form, 3fold stimulation of hydrophilic enzyme form | Homo sapiens | |
KM Value [mM]
| EC Number | KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
|---|---|---|---|---|---|---|
| 3.1.3.1 | 0.02 | - |
p-nitrophenyl phosphate | pH 9.0, hydrophilic and amphiphilic enzyme form | Homo sapiens | |
| 3.1.3.1 | 4.48 | - |
p-nitrophenyl phosphate | pH 10.3, hydrophilic enzyme form | Homo sapiens | |
| 3.1.3.1 | 5.02 | - |
p-nitrophenyl phosphate | pH 10.3, amphiphilic enzyme form | Homo sapiens | |
Localization
| EC Number | Localization | Comment | Organism | GeneOntology No. | Textmining |
|---|---|---|---|---|---|
| 3.1.3.1 | membrane | covalent attachment of the hydrophobic phosphatidylinositol membrane anchor causes the amphiphilic form to behave anomalously on electrophoresis | Homo sapiens | 16020 | - |
Molecular Weight [Da]
| EC Number | Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
|---|---|---|---|---|
| 3.1.3.1 | 214000 | - |
hydrophilic enzyme form, gradient gel electrophoresis | Homo sapiens |
| 3.1.3.1 | 255000 | - |
hydrophilic enzyme form, gel filtration | Homo sapiens |
Organism
| EC Number | Organism | UniProt | Comment | Textmining |
|---|---|---|---|---|
| 3.1.3.1 | Homo sapiens | - |
- |
- |
Source Tissue
| EC Number | Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|---|
| 3.1.3.1 | liver | amphiphilic and hydrophilic enzyme form | Homo sapiens | - |
Substrates and Products (Substrate)
| EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|---|
| 3.1.3.1 | p-nitrophenyl phosphate + H2O | - |
Homo sapiens | p-nitrophenol + phosphate | - |
? | |
Use of this online version of BRENDA is free under the CC BY 4.0 license. See terms of use for full details.
Release 2023.1 (January 2023)
Legal
Curated at
Member of
