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Literature summary extracted from

  • Takahashi, M.; Banno, Y.; Shikano, Y.; Mori, S.; Nozawa, Y.
    Purification and characterization of lysophospholipase-transacylase of pathogenic fungus Candida albicans (1991), Biochim. Biophys. Acta, 1082, 161-169.
    View publication on PubMed

Activating Compound

EC Number Activating Compound Comment Organism Structure
3.1.1.5 palmitoylcarnitine stimulates hydrolase activity Candida albicans

Inhibitors

EC Number Inhibitors Comment Organism Structure
3.1.1.5 L-palmitoylcarnitine inhibits phosphatidylcholine formation Candida albicans

KM Value [mM]

EC Number KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
3.1.1.5 0.076
-
 1-palmitoyl-sn-glycero-3-phosphatidylcholine
-
 Candida albicans

Molecular Weight [Da]

EC Number Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
3.1.1.5 41000
-
 1 * 41000, SDS-PAGE Candida albicans
3.1.1.5 49000
-
 gel filtration Candida albicans

Organism

EC Number Organism UniProt Comment Textmining
3.1.1.5 Candida albicans
-
-
-

Purification (Commentary)

EC Number Purification (Comment) Organism
3.1.1.5
-
 Candida albicans

Source Tissue

EC Number Source Tissue Comment Organism Textmining
3.1.1.5 culture medium
-
 Candida albicans
-

Specific Activity [micromol/min/mg]

EC Number Specific Activity Minimum [µmol/min/mg] Specific Activity Maximum [µmol/min/mg] Comment Organism
3.1.1.5 77.68
-
 hydrolase activity Candida albicans
3.1.1.5 320.9
-
 transacylase activity Candida albicans

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
3.1.1.5 1-acyl-lysophosphatidylcholine + 1-alkyllysophosphatidylcholine
-
 Candida albicans 1-alkyl-2-acyl-phosphatidylcholine + glycerylphosphocholine
-
 ?
3.1.1.5 1-palmitoyl-sn-glycero-3-phosphocholine + H2O
-
 Candida albicans palmitic acid + glycero-3-phosphocholine
-
 ?
3.1.1.5 lysophosphatidylcholine + H2O
-
 Candida albicans glycerophosphorylcholine + unesterified fatty acid
-
 ?
3.1.1.5 lysophosphatidylcholine + lysophosphatidylcholine
-
 Candida albicans glycerophosphocholine + phosphatidylcholine
-
 ?

Subunits

EC Number Subunits Comment Organism
3.1.1.5 monomer 1 * 41000, SDS-PAGE Candida albicans

Synonyms

EC Number Synonyms Comment Organism
3.1.1.5 lysophospholipase-transacylase
-
 Candida albicans

pH Optimum

EC Number pH Optimum Minimum pH Optimum Maximum Comment Organism
3.1.1.5 6
-
-
 Candida albicans

pH Range

EC Number pH Minimum pH Maximum Comment Organism
3.1.1.5 4 7 pH 4.0: about 45% of maximal activity, pH 7.0: about 85% of maximal activity, lysophosphatidylcholine transacylase activity, pH 4.0: about 50% of maximal activity, pH 7.0: about 80% of maximal activity, lysophosphatidyl hydrolase activity Candida albicans