BRENDA - Enzyme Database

Substrate specificity of two cationic lipases with high phospholipase A1 activity purified from guinea pig pancreas. II. Studies on glycerophospholipids

Fauvel, J.; Chap, H.; Roques, V.; Douste-Blazy, L.; Biochim. Biophys. Acta 792, 72-78 (1984)

Data extracted from this reference:

Activating Compound
EC Number
Activating Compound
Commentary
Organism
Structure
3.1.1.32
sodium deoxycholate
activates
Cavia porcellus
Organism
EC Number
Organism
Primary Accession No. (UniProt)
Commentary
Textmining
3.1.1.32
Cavia porcellus
-
two cationic phospholipase A1 activities
-
Source Tissue
EC Number
Source Tissue
Commentary
Organism
Textmining
3.1.1.32
pancreas
-
Cavia porcellus
-
Storage Stability
EC Number
Storage Stability
Organism
3.1.1.32
-20C, Tris-HCl buffer, pH 9.0, complete loss of activity after 1 month
Cavia porcellus
Substrates and Products (Substrate)
EC Number
Substrates
Commentary Substrates
Literature (Substrates)
Organism
Products
Commentary (Products)
Literature (Products)
Organism (Products)
Reversibility
3.1.1.32
1-acyl-sn-glycero-3-phosphocholine + H2O
-
94303
Cavia porcellus
fatty acid + glycero-3-phosphocholine
-
-
-
?
3.1.1.32
2-acyl-sn-glycero-3-phosphocholine + H2O
-
94303
Cavia porcellus
fatty acid + glycerophosphocholine
-
-
-
?
3.1.1.32
additional information
natural glycerophospholipids carrying a 1-acyl-bond are degraded in the following decreasing order of decreasing activity: phosphatidylcholine, phosphatidylinositol, 1-acyl-sn-glycero-3-phosphocholine, phosphatidylethanolamine, phosphatidylglycerol
94303
Cavia porcellus
?
-
-
-
-
3.1.1.32
additional information
no activity with 1-alkyl-2-acyl-sn-glycero-3-phosphocholine
94303
Cavia porcellus
?
-
-
-
-
3.1.1.32
phosphatidylcholine + H2O
-
94303
Cavia porcellus
?
-
-
-
?
3.1.1.32
phosphatidylethanolamine + H2O
-
94303
Cavia porcellus
?
-
-
-
?
3.1.1.32
phosphatidylglycerol + H2O
-
94303
Cavia porcellus
?
-
-
-
?
3.1.1.32
phosphatidylinositol + H2O
-
94303
Cavia porcellus
?
-
-
-
?
Activating Compound (protein specific)
EC Number
Activating Compound
Commentary
Organism
Structure
3.1.1.32
sodium deoxycholate
activates
Cavia porcellus
Source Tissue (protein specific)
EC Number
Source Tissue
Commentary
Organism
Textmining
3.1.1.32
pancreas
-
Cavia porcellus
-
Storage Stability (protein specific)
EC Number
Storage Stability
Organism
3.1.1.32
-20C, Tris-HCl buffer, pH 9.0, complete loss of activity after 1 month
Cavia porcellus
Substrates and Products (Substrate) (protein specific)
EC Number
Substrates
Commentary Substrates
Literature (Substrates)
Organism
Products
Commentary (Products)
Literature (Products)
Organism (Products)
Reversibility
3.1.1.32
1-acyl-sn-glycero-3-phosphocholine + H2O
-
94303
Cavia porcellus
fatty acid + glycero-3-phosphocholine
-
-
-
?
3.1.1.32
2-acyl-sn-glycero-3-phosphocholine + H2O
-
94303
Cavia porcellus
fatty acid + glycerophosphocholine
-
-
-
?
3.1.1.32
additional information
natural glycerophospholipids carrying a 1-acyl-bond are degraded in the following decreasing order of decreasing activity: phosphatidylcholine, phosphatidylinositol, 1-acyl-sn-glycero-3-phosphocholine, phosphatidylethanolamine, phosphatidylglycerol
94303
Cavia porcellus
?
-
-
-
-
3.1.1.32
additional information
no activity with 1-alkyl-2-acyl-sn-glycero-3-phosphocholine
94303
Cavia porcellus
?
-
-
-
-
3.1.1.32
phosphatidylcholine + H2O
-
94303
Cavia porcellus
?
-
-
-
?
3.1.1.32
phosphatidylethanolamine + H2O
-
94303
Cavia porcellus
?
-
-
-
?
3.1.1.32
phosphatidylglycerol + H2O
-
94303
Cavia porcellus
?
-
-
-
?
3.1.1.32
phosphatidylinositol + H2O
-
94303
Cavia porcellus
?
-
-
-
?