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Literature summary extracted from
- Subcellular localization and some properties of monoacylglycerol lipase in rat adipocytes (1981), J. Biochem., 90, 1413-1419.
Activating Compound
| EC Number | Activating Compound | Comment | Organism | Structure |
|---|---|---|---|---|
| 3.1.1.23 | EDTA | activates | Rattus norvegicus |  |
| 3.1.1.23 | EGTA | activates | Rattus norvegicus | |
Inhibitors
| EC Number | Inhibitors | Comment | Organism | Structure |
|---|---|---|---|---|
| 3.1.1.23 | Ca2+ | - |
Rattus norvegicus | |
| 3.1.1.23 | diisopropyl fluorophosphate | - |
Rattus norvegicus | |
| 3.1.1.23 | dithiothreitol | - |
Rattus norvegicus | |
| 3.1.1.23 | Mg2+ | - |
Rattus norvegicus | |
| 3.1.1.23 | NaCl | - |
Rattus norvegicus | |
| 3.1.1.23 | NaF | - |
Rattus norvegicus | |
| 3.1.1.23 | NEM | - |
Rattus norvegicus | |
| 3.1.1.23 | PCMB | - |
Rattus norvegicus | |
| 3.1.1.23 | Protamine sulfate | - |
Rattus norvegicus | |
| 3.1.1.23 | sodium cholate | - |
Rattus norvegicus | |
Localization
| EC Number | Localization | Comment | Organism | GeneOntology No. | Textmining |
|---|---|---|---|---|---|
| 3.1.1.23 | cytosol | - |
Rattus norvegicus | 5829 | - |
| 3.1.1.23 | plasma membrane | - |
Rattus norvegicus | 5886 | - |
Organism
| EC Number | Organism | UniProt | Comment | Textmining |
|---|---|---|---|---|
| 3.1.1.23 | Rattus norvegicus | - |
- |
- |
Source Tissue
| EC Number | Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|---|
| 3.1.1.23 | adipocyte | - |
Rattus norvegicus | - |
Storage Stability
| EC Number | Storage Stability | Organism |
|---|---|---|
| 3.1.1.23 | -20°C, 20% glycerol, 2 weeks, 25% loss of activity of the plasma membrane enzyme, no loss of activity of the cytosolic enzyme | Rattus norvegicus |
Substrates and Products (Substrate)
| EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|---|
| 3.1.1.23 | 1(3)-monooleoylglycerol + H2O | - |
Rattus norvegicus | oleic acid + glycerol | - |
? | |
| 3.1.1.23 | 2-monooleoylglycerol + H2O | - |
Rattus norvegicus | oleic acid + glycerol | - |
? | |
pH Optimum
| EC Number | pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
|---|---|---|---|---|
| 3.1.1.23 | 7 | 9 | - |
Rattus norvegicus |
pH Range
| EC Number | pH Minimum | pH Maximum | Comment | Organism |
|---|---|---|---|---|
| 3.1.1.23 | 5 | 9.5 | pH 5.0: about 55% of maximal activity, pH 9.5: about 85% of maximal activity, enzyme from cytosol | Rattus norvegicus |
| 3.1.1.23 | 6 | 9.5 | pH 6.0: about 45% of maximal activity, pH 9.5: about 65% of maximal activity, enzyme from plasma membrane | Rattus norvegicus |
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