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Literature summary extracted from
- Proteins of the kidney microvillar membrane. The amphipathic forms of endopeptidase purified from pig kidneys (1983), Biochem. J., 211, 743-753.
Inhibitors
| EC Number | Inhibitors | Comment | Organism | Structure |
|---|---|---|---|---|
| 3.4.24.11 | 1,10-phenanthroline | - |
Sus scrofa |  |
| 3.4.24.11 | 2,3-Dimercaptopropan-1-ol | weak | Sus scrofa | |
| 3.4.24.11 | dithiothreitol | weak | Sus scrofa | |
| 3.4.24.11 | EDTA | - |
Sus scrofa | |
| 3.4.24.11 | phosphoramidon | - |
Sus scrofa | |
| 3.4.24.11 | puromycin | - |
Sus scrofa | |
| 3.4.24.11 | thiorphan | - |
Sus scrofa | |
KM Value [mM]
| EC Number | KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
|---|---|---|---|---|---|---|
| 3.4.24.11 | 0.0685 | - |
glutaryl-Gly-Gly-Phe-2-naphthylamide | - |
Sus scrofa | |
Metals/Ions
| EC Number | Metals/Ions | Comment | Organism | Structure |
|---|---|---|---|---|
| 3.4.24.11 | Zinc | kidney enzyme contains 1 Zn atom per subunit | Sus scrofa | |
Molecular Weight [Da]
| EC Number | Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
|---|---|---|---|---|
| 3.4.24.11 | 89000 | - |
x * 89000, kidney enzyme, SDS-PAGE | Sus scrofa |
| 3.4.24.11 | 320000 | - |
kidney enzyme, gel filtration | Sus scrofa |
Organism
| EC Number | Organism | UniProt | Comment | Textmining |
|---|---|---|---|---|
| 3.4.24.11 | Sus scrofa | - |
- |
- |
Posttranslational Modification
| EC Number | Posttranslational Modification | Comment | Organism |
|---|---|---|---|
| 3.4.24.11 | side-chain modification | kidney enzyme contains 15% carbohydrate, if glucose is excluded | Sus scrofa |
Purification (Commentary)
| EC Number | Purification (Comment) | Organism |
|---|---|---|
| 3.4.24.11 | - |
Sus scrofa |
Source Tissue
| EC Number | Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|---|
| 3.4.24.11 | kidney | cortex | Sus scrofa | - |
Substrates and Products (Substrate)
| EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|---|
| 3.4.24.11 | glutaryl-Gly-Gly-Phe-2-naphthylamide + H2O | - |
Sus scrofa | glutaryl-Gly-Gly + Phe-2-naphthylamide | - |
? | |
Subunits
| EC Number | Subunits | Comment | Organism |
|---|---|---|---|
| 3.4.24.11 | ? | x * 89000, kidney enzyme, SDS-PAGE | Sus scrofa |
Turnover Number [1/s]
| EC Number | Turnover Number Minimum [1/s] | Turnover Number Maximum [1/s] | Substrate | Comment | Organism | Structure |
|---|---|---|---|---|---|---|
| 3.4.24.11 | 43.7 | - |
glutaryl-Gly-Gly-Phe-2-naphthylamide | - |
Sus scrofa | |
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