Literature summary extracted from

Relton, J.M.; Gee, N.S.; Matsas, R.; Turner, A.J.; Kenny, A.J.
Purification of endopeptidase-24.11 ( enkephalinase ) from pig brain by immunoadsorbent chromatography (1983), Biochem. J., 215, 519-523.

KM Value [mM]

EC Number	KM Value [mM]	KM Value Maximum [mM]	Substrate	Comment	Organism	Structure
3.4.24.11	0.104	-	D-Ala2-Leu5-enkephalin	-	Sus scrofa

Molecular Weight [Da]

EC Number	Molecular Weight [Da]	Molecular Weight Maximum [Da]	Comment	Organism
3.4.24.11	87000	-	x * 87000, brain enzyme, SDS-PAGE	Sus scrofa
3.4.24.11	280000	-	brain enzyme, gel filtration	Sus scrofa

Organism

EC Number	Organism	UniProt	Comment	Textmining
3.4.24.11	Sus scrofa	-	-	-

Posttranslational Modification

EC Number	Posttranslational Modification	Comment	Organism
3.4.24.11	side-chain modification	brain enzyme contains 13% carbohydrate, if glucose is excluded	Sus scrofa

Purification (Commentary)

EC Number	Purification (Comment)	Organism
3.4.24.11	-	Sus scrofa

Source Tissue

EC Number	Source Tissue	Comment	Organism	Textmining
3.4.24.11	brain	-	Sus scrofa	-

Specific Activity [micromol/min/mg]

EC Number	Specific Activity Minimum [µmol/min/mg]	Specific Activity Maximum [µmol/min/mg]	Comment	Organism
3.4.24.11	0.158	-	hydrolysis of insulin B-chain	Sus scrofa
3.4.24.11	26.3	-	hydrolysis of D-Ala2-Leu5-enkephalin	Sus scrofa

Substrates and Products (Substrate)

EC Number	Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
3.4.24.11	D-Ala2-Leu5-enkephalin + H2O	i.e. Tyr-D-Ala-Gly-Phe-Leu	Sus scrofa	Tyr-D-Ala-Gly + Phe-Leu	-	?

Subunits

EC Number	Subunits	Comment	Organism
3.4.24.11	?	x * 87000, brain enzyme, SDS-PAGE	Sus scrofa

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Release 2023.1 (January 2023)