Literature summary extracted from

Kanazawa, M.; Casley, D.J.; Sybertz, E.J.; Haslanger, M.F.; Johnston, C.I.
Localization and characterization of neutral metalloendopeptidase (EC 3.4.24.11), the degradative enzyme for atrial natriuretic peptide, in rat kidney using a radioiodinated neutral metalloendopeptidase inhibitor (1992), J. Pharmacol. Exp. Ther., 261, 1231-1237.

Inhibitors

EC Number	Inhibitors	Comment	Organism	Structure
3.4.24.11	EDTA	-	Rattus norvegicus
3.4.24.11	N-[N-[1(5)-carboxy-3-(4-hydroxyphenyl)propyl]-(5)-phenylalanyl]-(5)-isoserine	-	Rattus norvegicus
3.4.24.11	SCH39370	-	Rattus norvegicus
3.4.24.11	SCH48446	i.e. the diiodo analog of N-[N-[1(5)-carboxy-3-(4-hydroxyphenyl)propyl]-(5)-phenylalanyl]-(5)-isoserine	Rattus norvegicus

Organism

EC Number	Organism	UniProt	Comment	Textmining
3.4.24.11	Rattus norvegicus	-	-	-

Source Tissue

EC Number	Source Tissue	Comment	Organism	Textmining
3.4.24.11	kidney	-	Rattus norvegicus	-

Substrates and Products (Substrate)

EC Number	Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
3.4.24.11	Atrial natriuretic factor + H2O	-	Rattus norvegicus	?	-	?

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Release 2023.1 (January 2023)