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Literature summary extracted from

  • Habraken, Y.; Verly, W.G.
    The DNA 3-phosphatase and 5-hydroxyl kinase of rat liver chromatin (1983), FEBS Lett., 160, 46-50.
    View publication on PubMed

Inhibitors

EC Number Inhibitors Comment Organism Structure
2.7.1.78 diphosphate
-
 Rattus norvegicus
2.7.1.78 phosphate
-
 Rattus norvegicus
2.7.1.78 sulfate
-
 Rattus norvegicus
3.1.3.32 EDTA
-
 Rattus norvegicus

Localization

EC Number Localization Comment Organism GeneOntology No. Textmining
2.7.1.78 chromatin
-
 Rattus norvegicus 785
-
3.1.3.32 chromatin
-
 Rattus norvegicus 785
-

Metals/Ions

EC Number Metals/Ions Comment Organism Structure
2.7.1.78 Mg2+
-
 Rattus norvegicus

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
3.1.3.32 3'-phopsho-5'-hydroxy-DNA Rattus norvegicus the enzyme is capable of converting a 3'-phosphate/5'-OH strand of nicked DNA, which is unreparable by DNA ligase into a reparable 3'-OH/5'-phosphate nick in double stranded DNA ?
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
2.7.1.78 Rattus norvegicus
-
 enzyme also has DNA 3'-phosphatase activity
-
3.1.3.32 Rattus norvegicus
-
-
-

Purification (Commentary)

EC Number Purification (Comment) Organism
2.7.1.78
-
 Rattus norvegicus
3.1.3.32
-
 Rattus norvegicus

Source Tissue

EC Number Source Tissue Comment Organism Textmining
2.7.1.78 liver
-
 Rattus norvegicus
-
3.1.3.32 liver
-
 Rattus norvegicus
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2.7.1.78 ATP + 5'-dephospho-DNA
-
 Rattus norvegicus ADP + 5'-phospho-DNA
-
 ?
2.7.1.78 additional information enzyme also has DNA 3'-phosphatase activity Rattus norvegicus ?
-
 ?
3.1.3.32 3'-phopsho-5'-hydroxy-DNA the enzyme is capable of converting a 3'-phosphate/5'-OH strand of nicked DNA, which is unreparable by DNA ligase into a reparable 3'-OH/5'-phosphate nick in double stranded DNA Rattus norvegicus ?
-
 ?

Synonyms

EC Number Synonyms Comment Organism
2.7.1.78 More enzyme also possesses a 3'-phosphatase activity Rattus norvegicus

Temperature Optimum [°C]

EC Number Temperature Optimum [°C] Temperature Optimum Maximum [°C] Comment Organism
2.7.1.78 37
-
 assay at Rattus norvegicus

pH Optimum

EC Number pH Optimum Minimum pH Optimum Maximum Comment Organism
2.7.1.78 8
-
 assay at Rattus norvegicus

Cofactor

EC Number Cofactor Comment Organism Structure
2.7.1.78 ATP dependent on Rattus norvegicus