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Literature summary extracted from
- beta-Hydroxy-beta-methylglutaryl coenzyme A deacylase (1958), J. Biol. Chem., 233, 434-438.
Localization
| EC Number | Localization | Comment | Organism | GeneOntology No. | Textmining |
|---|---|---|---|---|---|
| 3.1.2.5 | cytosol | - |
Gallus gallus | 5829 | - |
Natural Substrates/ Products (Substrates)
| EC Number | Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
|---|---|---|---|---|---|---|---|
| 3.1.2.5 | (S)-3-hydroxy-3-methylglutaryl-CoA + H2O | Gallus gallus | - |
? | - |
? |  |
| 3.1.2.5 | (S)-3-hydroxy-3-methylglutaryl-CoA + H2O | Escherichia coli | - |
? | - |
? | |
| 3.1.2.5 | (S)-3-hydroxy-3-methylglutaryl-CoA + H2O | Sus scrofa | - |
? | - |
? | |
| 3.1.2.5 | (S)-3-hydroxy-3-methylglutaryl-CoA + H2O | Tetrahymena pyriformis | - |
? | - |
? | |
| 3.1.2.5 | (S)-3-hydroxy-3-methylglutaryl-CoA + H2O | Neurospora crassa | - |
? | - |
? | |
Organism
| EC Number | Organism | UniProt | Comment | Textmining |
|---|---|---|---|---|
| 3.1.2.5 | Escherichia coli | - |
- |
- |
| 3.1.2.5 | Gallus gallus | - |
- |
- |
| 3.1.2.5 | Neurospora crassa | - |
- |
- |
| 3.1.2.5 | Sus scrofa | - |
- |
- |
| 3.1.2.5 | Tetrahymena pyriformis | - |
- |
- |
Source Tissue
| EC Number | Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|---|
| 3.1.2.5 | brain | - |
Sus scrofa | - |
| 3.1.2.5 | kidney | - |
Sus scrofa | - |
| 3.1.2.5 | liver | - |
Gallus gallus | - |
| 3.1.2.5 | liver | - |
Sus scrofa | - |
Substrates and Products (Substrate)
| EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|---|
| 3.1.2.5 | (S)-3-hydroxy-3-methylglutaryl-CoA + H2O | - |
Gallus gallus | CoA + 3-hydroxy-3-methylglutarate | - |
? | |
| 3.1.2.5 | (S)-3-hydroxy-3-methylglutaryl-CoA + H2O | - |
Escherichia coli | CoA + 3-hydroxy-3-methylglutarate | - |
? | |
| 3.1.2.5 | (S)-3-hydroxy-3-methylglutaryl-CoA + H2O | - |
Sus scrofa | CoA + 3-hydroxy-3-methylglutarate | - |
? | |
| 3.1.2.5 | (S)-3-hydroxy-3-methylglutaryl-CoA + H2O | - |
Tetrahymena pyriformis | CoA + 3-hydroxy-3-methylglutarate | - |
? | |
| 3.1.2.5 | (S)-3-hydroxy-3-methylglutaryl-CoA + H2O | - |
Neurospora crassa | CoA + 3-hydroxy-3-methylglutarate | - |
? | |
| 3.1.2.5 | (S)-3-hydroxy-3-methylglutaryl-CoA + H2O | - |
Gallus gallus | ? | - |
? | |
| 3.1.2.5 | (S)-3-hydroxy-3-methylglutaryl-CoA + H2O | - |
Escherichia coli | ? | - |
? | |
| 3.1.2.5 | (S)-3-hydroxy-3-methylglutaryl-CoA + H2O | - |
Sus scrofa | ? | - |
? | |
| 3.1.2.5 | (S)-3-hydroxy-3-methylglutaryl-CoA + H2O | - |
Tetrahymena pyriformis | ? | - |
? | |
| 3.1.2.5 | (S)-3-hydroxy-3-methylglutaryl-CoA + H2O | - |
Neurospora crassa | ? | - |
? | |
Temperature Optimum [°C]
| EC Number | Temperature Optimum [°C] | Temperature Optimum Maximum [°C] | Comment | Organism |
|---|---|---|---|---|
| 3.1.2.5 | 37 | - |
assay at | Gallus gallus |
pH Optimum
| EC Number | pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
|---|---|---|---|---|
| 3.1.2.5 | 7.8 | - |
soluble | Gallus gallus |
pH Range
| EC Number | pH Minimum | pH Maximum | Comment | Organism |
|---|---|---|---|---|
| 3.1.2.5 | 6 | 9 | - |
Gallus gallus |
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Release 2023.1 (January 2023)
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