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Literature summary extracted from

  • Holmlund, C.E.; Blank, R.H.
    Preparation and properties of a steroid lactonase (1965), Arch. Biochem. Biophys., 109, 29-35.
    View publication on PubMed

Inhibitors

EC Number Inhibitors Comment Organism Structure
3.1.1.37 HgCl2
-
 Acremonium chrysogenum
3.1.1.37 p-chloromercuriphenylsulfonate
-
 Acremonium chrysogenum

Metals/Ions

EC Number Metals/Ions Comment Organism Structure
3.1.1.37 Mg2+ optimum: 0.1 M, enhances Acremonium chrysogenum
3.1.1.37 Mn2+ optimum: 0.1 M, enhances Acremonium chrysogenum

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
3.1.1.37 testololactone + H2O Acremonium chrysogenum
-
 ?
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
3.1.1.37 Acremonium chrysogenum
-
-
-

Purification (Commentary)

EC Number Purification (Comment) Organism
3.1.1.37
-
 Acremonium chrysogenum

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
3.1.1.37 16alpha-hydroxytestololactone + H2O 50% the rate of testololactone Acremonium chrysogenum 16alpha-hydroxytestolate
-
 ?
3.1.1.37 additional information not: steroids containing gamma-lactones, digitoxigenin, spirolactone Acremonium chrysogenum ?
-
 ?
3.1.1.37 testolate lactone formation more rapidly than lactone hydrolysis, only at pH 6, presence of Mn2+ Acremonium chrysogenum testololactone + H2O
-
 r
3.1.1.37 testololactone + H2O
-
 Acremonium chrysogenum testolate
-
 r
3.1.1.37 testololactone + H2O
-
 Acremonium chrysogenum ?
-
 ?