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Literature summary extracted from
- Isolation, molecular properties, and kinetic characterization of lipoprotein lipase from rat heart (1977), J. Biol. Chem., 252, 4202-4209.
Activating Compound
| EC Number | Activating Compound | Comment | Organism | Structure |
|---|---|---|---|---|
| 3.1.1.34 | apolipoprotein C-II | required | Rattus norvegicus | |
| 3.1.1.34 | heparin | increases hydrolytic activity | Rattus norvegicus |  |
Inhibitors
| EC Number | Inhibitors | Comment | Organism | Structure |
|---|---|---|---|---|
| 3.1.1.34 | apolipoprotein C I | - |
Rattus norvegicus | |
| 3.1.1.34 | apolipoprotein C III | - |
Rattus norvegicus | |
| 3.1.1.34 | diisopropyl fluorophosphate | - |
Rattus norvegicus | |
| 3.1.1.34 | NaCl | 0.5 M, 80% inhibition, 1 M, 90% inhibition | Rattus norvegicus | |
| 3.1.1.34 | phenylmethylsulfonyl fluoride | - |
Rattus norvegicus | |
Molecular Weight [Da]
| EC Number | Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
|---|---|---|---|---|
| 3.1.1.34 | 34000 | - |
x * 34000, SDS-PAGE, equilibrium sedimentation in presence of 6 M guanidine HCl and 0.1% mercaptoethanol | Rattus norvegicus |
Organism
| EC Number | Organism | UniProt | Comment | Textmining |
|---|---|---|---|---|
| 3.1.1.34 | Rattus norvegicus | - |
- |
- |
Posttranslational Modification
| EC Number | Posttranslational Modification | Comment | Organism |
|---|---|---|---|
| 3.1.1.34 | side-chain modification | glycoprotein | Rattus norvegicus |
Purification (Commentary)
| EC Number | Purification (Comment) | Organism |
|---|---|---|
| 3.1.1.34 | - |
Rattus norvegicus |
Source Tissue
| EC Number | Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|---|
| 3.1.1.34 | heart | - |
Rattus norvegicus | - |
Specific Activity [micromol/min/mg]
| EC Number | Specific Activity Minimum [µmol/min/mg] | Specific Activity Maximum [µmol/min/mg] | Comment | Organism |
|---|---|---|---|---|
| 3.1.1.34 | 10.77 | - |
- |
Rattus norvegicus |
Substrates and Products (Substrate)
| EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|---|
| 3.1.1.34 | additional information | no absolute specificity for monolayers of triglycerides, hydrolysis of diglyceride monolayers at comparable rates | Rattus norvegicus | ? | - |
? | |
| 3.1.1.34 | trioctanoin + H2O | - |
Rattus norvegicus | ? | - |
? | |
| 3.1.1.34 | triolein + H2O | - |
Rattus norvegicus | ? | - |
? | |
Subunits
| EC Number | Subunits | Comment | Organism |
|---|---|---|---|
| 3.1.1.34 | ? | x * 34000, SDS-PAGE, equilibrium sedimentation in presence of 6 M guanidine HCl and 0.1% mercaptoethanol | Rattus norvegicus |
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