EC Number | Inhibitors | Comment | Organism | Structure |
---|---|---|---|---|
1.8.1.12 | benzimidazole | - |
Trypanosoma cruzi | |
1.8.1.12 | chlorpromazine | - |
Trypanosoma cruzi | |
1.8.1.12 | cis-3-oxo-8,9b-bis-(trans-N1-(acrylamidospermidyl))-1,2,3,4,4a,9b-hexahydrodibenzofuran | - |
Trypanosoma cruzi | |
1.8.1.12 | clomipramine | - |
Trypanosoma cruzi | |
1.8.1.12 | indrataline | - |
Trypanosoma cruzi | |
1.8.1.12 | lunarine | - |
Trypanosoma cruzi | |
1.8.1.12 | N1,N4-bis(3-aminopropyl)-N1-(10,11-dihydro-5H-dibenzo[a,d][7]annulen-10-yl)-N4-(10,11-dihydro-5H-dibenzo[a,d][7]annulen-5-yl)butane-1,4-diamine | - |
Trypanosoma cruzi | |
1.8.1.12 | N1-(3-aminopropyl)-N1-(10,11-dihydro-5H-dibenzo[a,d][7]annulen-10-yl)butane-1,4-diamine | - |
Trypanosoma cruzi | |
1.8.1.12 | N1-(3-aminopropyl)-N1-(10,11-dihydro-5H-dibenzo[a,d][7]annulen-10-yl)propane-1,3-diamine | - |
Trypanosoma cruzi | |
1.8.1.12 | prochlorperazine | - |
Trypanosoma cruzi | |
1.8.1.12 | Quinazoline | - |
Trypanosoma cruzi | |
1.8.1.12 | thioridazine | potent irreversible inhibitor. 100% inhibition at 0.010 mM | Trypanosoma cruzi | |
1.8.1.12 | triflupromizine | - |
Trypanosoma cruzi |
EC Number | Organism | UniProt | Comment | Textmining |
---|---|---|---|---|
1.8.1.12 | Trypanosoma cruzi | P28593 | - |
- |
EC Number | Synonyms | Comment | Organism |
---|---|---|---|
1.8.1.12 | trypanothione reductase | - |
Trypanosoma cruzi |
EC Number | Ki Value [mM] | Ki Value maximum [mM] | Inhibitor | Comment | Organism | Structure |
---|---|---|---|---|---|---|
1.8.1.12 | 0.0065 | - |
clomipramine | pH and temperature not specified in the publication | Trypanosoma cruzi |
EC Number | IC50 Value | IC50 Value Maximum | Comment | Organism | Inhibitor | Structure |
---|---|---|---|---|---|---|
1.8.1.12 | 0.0038 | - |
pH and temperature not specified in the publication | Trypanosoma cruzi | clomipramine | |
1.8.1.12 | 0.0063 | - |
pH and temperature not specified in the publication | Trypanosoma cruzi | chlorpromazine | |
1.8.1.12 | 0.0074 | - |
pH and temperature not specified in the publication | Trypanosoma cruzi | prochlorperazine | |
1.8.1.12 | 0.0075 | - |
pH and temperature not specified in the publication | Trypanosoma cruzi | triflupromizine |