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Literature summary extracted from

  • MacCabe,A.; Sanmartin, G.; Orejas, M.
    Identification of the genes encoding the catalytic steps corresponding to LRA4 (l-2-keto-3-deoxyrhamnonate aldolase) and L-lactaldehyde dehydrogenase in Aspergillus nidulans evidence for involvement of the loci AN9425/lraD and AN0544/aldA in the l-rhamnose catabolic pathway (2021), Environ. Microbiol., 2021, 2420-2432 .
    View publication on PubMed

Organism

EC Number Organism UniProt Comment Textmining
1.2.1.22 Aspergillus nidulans A0A1U8QKS3
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1.2.1.22 Aspergillus nidulans ATCC 38163 A0A1U8QKS3
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4.1.2.53 Aspergillus nidulans A0A1U8QYE1
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4.1.2.53 Aspergillus nidulans ATCC 38163 A0A1U8QYE1
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Synonyms

EC Number Synonyms Comment Organism
1.2.1.22 AldA
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Aspergillus nidulans
1.2.1.22 AN0544 locus name Aspergillus nidulans
1.2.1.22 L-lactaldehyde dehydrogenase
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Aspergillus nidulans
4.1.2.53 AN9425 locus name Aspergillus nidulans
4.1.2.53 L-2-keto-3-deoxyrhamnonate aldolase
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Aspergillus nidulans
4.1.2.53 LRA4
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Aspergillus nidulans

Expression

EC Number Organism Comment Expression
1.2.1.22 Aspergillus nidulans expression is induced on L-rhamnose via the transcriptional activator RhaR. The relative contribution of RhaR to the induction of aldA is the same as that for its induction of the LraA-LraC and rhamnosidase genes up
4.1.2.53 Aspergillus nidulans expression is induced on L-rhamnose via the transcriptional activator RhaR up

General Information

EC Number General Information Comment Organism
1.2.1.22 physiological function a loss-of-function mutation severely impairs L-rhamnose utilization Aspergillus nidulans
4.1.2.53 physiological function an AN9425 deletion mutant shows pseudo-wild type growth on L-rhamnose MM agar plates. Upon growth on 1% L-rhamnose as sole carbon source, the deletion mutant shows a reduced colour intensity of the sporulation zone Aspergillus nidulans