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Literature summary extracted from

  • Nakamura, S.; Pourkheirandish, M.; Morishige, H.; Kubo, Y.; Nakamura, M.; Ichimura, K.; Seo, S.; Kanamori, H.; Wu, J.; Ando, T.; Hensel, G.; Sameri, M.; Stein, N.; Sato, K.; Matsumoto, T.; Yano, M.; Komatsuda, T.
    Mitogen-activated protein kinase kinase 3 regulates seed dormancy in barley (2016), Curr. Biol., 26, 775-781 .
    View publication on PubMed

Application

EC Number Application Comment Organism
2.7.12.2 agriculture quantitative trait locus Qsd2-AK at SD2 is the single major determinant explaining the difference in seed dormancy between the dormant cultivar Azumamugi (Az) and the nondormant cultivar Kanto Nakate Gold (KNG). The dormant Az allele of MKK3 is recessive, the N260T substitution in this allele decreases MKK3 kinase activity and appears to be causal for Qsd2-AK. The N260T substitution occurs in the immediate ancestor allele of the dormant allele, and the established dormant allele became prevalent in barley cultivars grown in East Asia, where the rainy season and harvest season often overlap Hordeum vulgare

Protein Variants

EC Number Protein Variants Comment Organism
2.7.12.2 N260T substitution decreases MKK3 kinase activity and appears to be causal for quantitiative trait locus Qsd2-AK Hordeum vulgare

Organism

EC Number Organism UniProt Comment Textmining
2.7.12.2 Hordeum vulgare A0A140JZ28
-
-

Source Tissue

EC Number Source Tissue Comment Organism Textmining

Synonyms

EC Number Synonyms Comment Organism
2.7.12.2 MKK3
-
 Hordeum vulgare

General Information

EC Number General Information Comment Organism
2.7.12.2 physiological function quantitative trait locus Qsd2-AK at SD2 is the single major determinant explaining the difference in seed dormancy between the dormant cultivar Azumamugi (Az) and the nondormant cultivar Kanto Nakate Gold (KNG). The dormant Az allele of MKK3 is recessive, the N260T substitution in this allele decreases MKK3 kinase activity and appears to be causal for Qsd2-AK. The N260T substitution occurs in the immediate ancestor allele of the dormant allele, and the established dormant allele became prevalent in barley cultivars grown in East Asia, where the rainy season and harvest season often overlap. Germination percentage of a loss of function mutant is reduced to 23% Hordeum vulgare