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Literature summary extracted from

  • Fu, M.M.; Liu, C.; Wu, F.
    Genome-wide identification, characterization and expression analysis of xyloglucan endotransglucosylase/hydrolase genes family in barley (Hordeum vulgare) (2019), Molecules, 24, 1935 .
    View publication on PubMedView publication on EuropePMC

Cloned(Commentary)

EC Number Cloned (Comment) Organism
2.4.1.207 24 XTH genes, HvXTH1-24, sequence comparisons and phylogenetic analysis, the 24 genes are unevenly distributed on the 7 chromosomes, with 10 of them specifically located on chromosome 7H, genetic organization, sequence comparisons and phylogenetic analysis, overview. Four gene pairs (HvXTH6/7, HvXTH17/18, HvXTH19/20, HvXTH21/22) are detected within 100 kb on chromosome 3H and chromosome 7H, which may be the result of tandem duplication Hordeum vulgare

Organism

EC Number Organism UniProt Comment Textmining
2.4.1.207 Hordeum vulgare
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cv. Morex
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Posttranslational Modification

EC Number Posttranslational Modification Comment Organism
2.4.1.207 glycoprotein all HvXTH protein members, except HvXTH15, have a conserved N-glycosylation site. The N-glycosylation site domain (NxT/S/Y) is thought to play a role in protein stability Hordeum vulgare

Source Tissue

EC Number Source Tissue Comment Organism Textmining
2.4.1.207 additional information expression profiles based on the barley genome database show that HvXTH family members display different expression patterns in different tissues and at different stages. Transcript levels of HvXTH isozymes in different tissues, overview Hordeum vulgare
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Subunits

EC Number Subunits Comment Organism
2.4.1.207 More isozymes domain structures, overview. Prediction of the secondary structures of the HvXTH isozyme proteins Hordeum vulgare

Synonyms

EC Number Synonyms Comment Organism
2.4.1.207 XTH
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Hordeum vulgare
2.4.1.207 xyloglucan endotransglucosylase/hydrolase
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Hordeum vulgare

General Information

EC Number General Information Comment Organism
2.4.1.207 evolution phylogenetic analysis shows that 24 HvXTH genes can be classified into three phylogenetic groups: (I/II, III-A and III-B) and HvXTH15 is in the ancestral group. Xyloglucan endotransglucosylase/hydrolases (XET/XEHs also named XTHs) are a family of xyloglucan modifying enzymes that have two different catalytic activities and can act either as endotransglucosylases (XET, EC 2.4.1.207) or as endohydrolases (XEH, EC 3.2.1.151). XTHs belong to glycoside hydrolase family 16. Each XTH possesses a highly conserved domain (ExDxE) responsible for catalytic activity. Four gene pairs (HvXTH6/7, HvXTH17/18, HvXTH19/20, HvXTH21/22) are detected within 100 kb on chromosome 3H and chromosome 7H, which may be the result of tandem duplication. According to the phylogenetic tree, HvXTH6 and HvXTH7 and HvXTH17/18/19/20 are closely related, which indicates that the gene duplications of these three pair of genes might be related. The active site (ExDxE) containing the residues responsible for catalytic activity is highly conserved in all of the HvXTH family members. The first glutamate residue acts as catalytic nucleophile which initiates the enzymatic reaction and the second one as a base to activate the substrate Hordeum vulgare
2.4.1.207 physiological function roles of HvXTH genes in the growth and development of barley, overview Hordeum vulgare