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Literature summary extracted from

  • Strumilo, S.; Bielska, M.; Kazaniecki, L.; Tylicki, A.
    Kinetic properties of pyruvate dehydrogenase and 2-oxoglutarate dehydrogenase complexes from a new source - the heart of wild boar Sus scrofa (2015), J. Evol. Biochem. Physiol., 51, 438-440 .
No PubMed abstract available

Activating Compound

EC Number Activating Compound Comment Organism Structure
1.2.1.105 ADP presence of ADP decreases the Km value about 2fold, 50% of maximum activation at 0.07 mM Sus scrofa

KM Value [mM]

EC Number KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
1.2.1.104 0.0043
-
 pyruvate domestic pig, pH 7.5, temperature not specified in the publication Sus scrofa
1.2.1.104 0.0153
-
 pyruvate wild boar, pH 7.5, temperature not specified in the publication Sus scrofa
1.2.1.104 0.019
-
 CoA domestic pig, pH 7.5, temperature not specified in the publication Sus scrofa
1.2.1.104 0.022
-
 NAD+ wild boar, pH 7.5, temperature not specified in the publication Sus scrofa
1.2.1.104 0.0336
-
 NAD+ domestic pig, pH 7.5, temperature not specified in the publication Sus scrofa
1.2.1.104 0.0761
-
 CoA wild boar, pH 7.5, temperature not specified in the publication Sus scrofa
1.2.1.105 0.0198
-
 CoA S0.5 value, pH 7.5, temperature not specified in the publication Sus scrofa
1.2.1.105 0.0249
-
 NAD+ S0.5 value, Hill coefficient 0.4, pH 7.5, temperature not specified in the publication Sus scrofa
1.2.1.105 0.251
-
 2-oxoglutarate S0.5 value, pH 7.5, temperature not specified in the publication Sus scrofa

Localization

EC Number Localization Comment Organism GeneOntology No. Textmining
1.2.1.104 mitochondrion
-
 Sus scrofa 5739
-
1.2.1.105 mitochondrion
-
 Sus scrofa 5739
-

Organism

EC Number Organism UniProt Comment Textmining
1.2.1.104 Sus scrofa
-
-
-
1.2.1.105 Sus scrofa
-
 wild boar
-

Source Tissue

EC Number Source Tissue Comment Organism Textmining
1.2.1.104 heart
-
 Sus scrofa
-
1.2.1.105 heart
-
 Sus scrofa
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
1.2.1.104 pyruvate + CoA + NAD+
-
 Sus scrofa acetyl-CoA + CO2 + NADH
-
 ?
1.2.1.105 2-oxoglutarate + CoA + NAD+
-
 Sus scrofa succinyl-CoA + CO2 + NADH
-
 ?