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Literature summary extracted from

  • Zhang, L.; Ren, L.; Shi, P.; Lu, D.; Zhao, C.; Su, X.; Zhang, L.; Huang, J.
    The immunological regulation roles of porcine beta-1,4 galactosyltransferase V (B4GALT5) in PRRSV infection (2018), Front. Cell. Infect. Microbiol., 8, 48 .
    View publication on PubMedView publication on EuropePMC

Application

EC Number Application Comment Organism
2.4.1.274 medicine B4GALT5 expression is upregulated in porcine reproductive and respiratory syndrome virus (PRRSV) infected porcine alveolar macrophage. The PRRSV proliferation is slightly inhibited by overexpression of B4GALT5. B4GALT5 and PRRSV protein GP5 colocalize in Golgi membrane. mRNA transcription, including inflammatory cytokines IFN-alpha, IL-6, IL-18, IL-1beta, TNF-alpha and some cell surface glycosylated proteins involved in antigen presentation (MHC-I/II), cell adhesion and migration (chemokine MCP-1 and receptor CCR2; LFA-1, ICAM-1) are upregulated in B4GALT5 overexpressing PRRSV infected cells Sus scrofa

Cloned(Commentary)

EC Number Cloned (Comment) Organism
2.4.1.274
-
 Sus scrofa

Organism

EC Number Organism UniProt Comment Textmining
2.4.1.274 Sus scrofa A0A1S6M251
-
-

Source Tissue

EC Number Source Tissue Comment Organism Textmining
2.4.1.274 macrophage alveolar mactrophage Sus scrofa
-

Synonyms

EC Number Synonyms Comment Organism
2.4.1.274 B4GalT5
-
 Sus scrofa

Expression

EC Number Organism Comment Expression
2.4.1.274 Sus scrofa B4GALT5 expression is upregulated in PRRSV infected porcine alveolar macrophage up