Literature summary extracted from

Leng, F.; Wu, L.Y.; Lu, C.; Pan, X.M.
Determinants of thermostability in serine hydroxymethyltransferase identified by principal component analysis (2017), Sci. Rep., 7, 46463 .

Natural Substrates/ Products (Substrates)

EC Number	Natural Substrates	Organism	Comment (Nat. Sub.)	Natural Products	Comment (Nat. Pro.)	Rev.	Reac.
2.1.2.1	5,10-methylenetetrahydrofolate + glycine + H2O	Geobacillus stearothermophilus	-	tetrahydrofolate + L-serine	-	r
2.1.2.1	tetrahydrofolate + L-serine	Geobacillus stearothermophilus	-	5,10-methylenetetrahydrofolate + glycine + H2O	-	r

Organism

EC Number	Organism	UniProt	Comment	Textmining
2.1.2.1	Geobacillus stearothermophilus	Q7SIB6	-	-

Substrates and Products (Substrate)

EC Number	Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
2.1.2.1	5,10-methylenetetrahydrofolate + glycine + H2O	-	Geobacillus stearothermophilus	tetrahydrofolate + L-serine	-	r
2.1.2.1	tetrahydrofolate + L-serine	-	Geobacillus stearothermophilus	5,10-methylenetetrahydrofolate + glycine + H2O	-	r

Synonyms

EC Number	Synonyms	Comment	Organism
2.1.2.1	serine hydroxymethyltransferase	-	Geobacillus stearothermophilus
2.1.2.1	SHMT	-	Geobacillus stearothermophilus

Cofactor

EC Number	Cofactor	Comment	Organism	Structure
2.1.2.1	pyridoxal 5'-phosphate	-	Geobacillus stearothermophilus

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Release 2023.1 (January 2023)