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Literature summary extracted from

  • McManus, T.J.; Wells, S.A.; Walker, A.B.
    Salt bridge impact on global rigidity and thermostability in thermophilic citrate synthase (2019), Phys. Biol., 17, 016002 .
    View publication on PubMed

Crystallization (Commentary)

EC Number Crystallization (Comment) Organism
2.3.3.16 comparison of rigidity in citrate synthases from thermophiles to investgate the relationship between rigidity and thermostability. The increase in rigidity does not detract from the functional flexibility of the active site in all systems once their respective temperature range has been reached. In hyperthermophiles, salt bridges have stabilising roles in the active site, occuring in close proximity to key residues involved in catalysis and binding of the protein Thermus thermophilus
2.3.3.16 comparison of rigidity in citrate synthases from thermophiles to investigate the relationship between rigidity and thermostability. The increase in rigidity does not detract from the functional flexibility of the active site in all systems once their respective temperature range has been reached. In hyperthermophiles, salt bridges have stabilising roles in the active site, occuring in close proximity to key residues involved in catalysis and binding of the protein Thermoplasma acidophilum
2.3.3.16 comparison of rigidity in citrate synthases from thermophiles to investigate the relationship between rigidity and thermostability. The increase in rigidity does not detract from the functional flexibility of the active site in all systems once their respective temperature range has been reached. In hyperthermophiles, salt bridges have stabilising roles in the active site, occuring in close proximity to key residues involved in catalysis and binding of the protein Saccharolobus solfataricus

Organism

EC Number Organism UniProt Comment Textmining
2.3.3.16 Saccharolobus solfataricus P80148
-
-
2.3.3.16 Saccharolobus solfataricus DSM 1617 P80148
-
-
2.3.3.16 Thermoplasma acidophilum P21553
-
-
2.3.3.16 Thermus thermophilus Q5SIM6
-
-
2.3.3.16 Thermus thermophilus DSM 579 Q5SIM6
-
-

Synonyms

EC Number Synonyms Comment Organism
2.3.3.16 TTHA1343
-
Thermus thermophilus