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Literature summary extracted from

  • Banerjee, A.; Bardhan, R.; Chowdhury, M.; Joardar, S.N.; Isore, D.P.; Batabyal, K.; Dey, S.; Sar, T.K.; Bandyopadhyay, S.; Dutta, T.K.; Samanta, I.
    Characterization of beta-lactamase and biofilm producing Enterobacteriaceae isolated from organized and backyard farm ducks (2019), Lett. Appl. Microbiol., 69, 110-115 .
    View publication on PubMed

Cloned(Commentary)

EC Number Cloned (Comment) Organism
3.5.2.6 genotyping and phenotyping of Escherichia coli strains with beta-lactamase activity in faeces from ducks Escherichia coli
3.5.2.6 genotyping and phenotyping of Klebsiella strains with beta-lactamase activity in faeces from ducks Klebsiella pneumoniae
3.5.2.6 genotyping and phenotyping of Salmonella strains with beta-lactamase activity in faeces from ducks Salmonella sp.

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
3.5.2.6 amikacin + H2O Escherichia coli
-
 ?
-
 ?
3.5.2.6 amikacin + H2O Klebsiella pneumoniae
-
 ?
-
 ?
3.5.2.6 amikacin + H2O Salmonella sp.
-
 ?
-
 ?
3.5.2.6 amoxicillin + H2O Escherichia coli
-
 (2R,4S)-2-[(R)-[[(2R)-2-amino-2-(4-hydroxyphenyl)acetyl]amino](carboxy)methyl]-5,5-dimethyl-1,3-thiazolidine-4-carboxylic acid
-
 ?
3.5.2.6 amoxicillin + H2O Klebsiella pneumoniae
-
 (2R,4S)-2-[(R)-[[(2R)-2-amino-2-(4-hydroxyphenyl)acetyl]amino](carboxy)methyl]-5,5-dimethyl-1,3-thiazolidine-4-carboxylic acid
-
 ?
3.5.2.6 amoxicillin + H2O Salmonella sp.
-
 (2R,4S)-2-[(R)-[[(2R)-2-amino-2-(4-hydroxyphenyl)acetyl]amino](carboxy)methyl]-5,5-dimethyl-1,3-thiazolidine-4-carboxylic acid
-
 ?
3.5.2.6 ampicillin + H2O Escherichia coli
-
 (2R,4S)-2-[(R)-[[(2R)-2-amino-2-phenylacetyl]amino](carboxy)methyl]-5,5-dimethyl-1,3-thiazolidine-4-carboxylic acid
-
 ?
3.5.2.6 ampicillin + H2O Klebsiella pneumoniae
-
 (2R,4S)-2-[(R)-[[(2R)-2-amino-2-phenylacetyl]amino](carboxy)methyl]-5,5-dimethyl-1,3-thiazolidine-4-carboxylic acid
-
 ?
3.5.2.6 ampicillin + H2O Salmonella sp.
-
 (2R,4S)-2-[(R)-[[(2R)-2-amino-2-phenylacetyl]amino](carboxy)methyl]-5,5-dimethyl-1,3-thiazolidine-4-carboxylic acid
-
 ?
3.5.2.6 cefotaxime + H2O Escherichia coli
-
 (2R)-5-[(acetyloxy)methyl]-2-[(R)-[[(2E)-2-(2-amino-1,3-thiazol-4-yl)-2-(methoxyimino)acetyl]amino](carboxy)methyl]-3,6-dihydro-2H-1,3-thiazine-4-carboxylic acid
-
 ?
3.5.2.6 cefotaxime + H2O Klebsiella pneumoniae
-
 (2R)-5-[(acetyloxy)methyl]-2-[(R)-[[(2E)-2-(2-amino-1,3-thiazol-4-yl)-2-(methoxyimino)acetyl]amino](carboxy)methyl]-3,6-dihydro-2H-1,3-thiazine-4-carboxylic acid
-
 ?
3.5.2.6 cefotaxime + H2O Salmonella sp.
-
 (2R)-5-[(acetyloxy)methyl]-2-[(R)-[[(2E)-2-(2-amino-1,3-thiazol-4-yl)-2-(methoxyimino)acetyl]amino](carboxy)methyl]-3,6-dihydro-2H-1,3-thiazine-4-carboxylic acid
-
 ?
3.5.2.6 ceftazidime + H2O Escherichia coli
-
 ?
-
 ?
3.5.2.6 ceftazidime + H2O Klebsiella pneumoniae
-
 ?
-
 ?
3.5.2.6 ceftazidime + H2O Salmonella sp.
-
 ?
-
 ?
3.5.2.6 ceftriaxone + H2O Escherichia coli
-
 ?
-
 ?
3.5.2.6 ceftriaxone + H2O Klebsiella pneumoniae
-
 ?
-
 ?
3.5.2.6 ceftriaxone + H2O Salmonella sp.
-
 ?
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
3.5.2.6 Escherichia coli
-
 isolated from faeces (cloacal swabs) of healthy ducks
-
3.5.2.6 Klebsiella pneumoniae
-
 isolated from faeces (cloacal swabs) of healthy ducks
-
3.5.2.6 Salmonella sp.
-
 isolated from faeces (cloacal swabs) of healthy ducks
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
3.5.2.6 amikacin + H2O
-
 Escherichia coli ?
-
 ?
3.5.2.6 amikacin + H2O
-
 Klebsiella pneumoniae ?
-
 ?
3.5.2.6 amikacin + H2O
-
 Salmonella sp. ?
-
 ?
3.5.2.6 amoxicillin + H2O
-
 Escherichia coli (2R,4S)-2-[(R)-[[(2R)-2-amino-2-(4-hydroxyphenyl)acetyl]amino](carboxy)methyl]-5,5-dimethyl-1,3-thiazolidine-4-carboxylic acid
-
 ?
3.5.2.6 amoxicillin + H2O
-
 Klebsiella pneumoniae (2R,4S)-2-[(R)-[[(2R)-2-amino-2-(4-hydroxyphenyl)acetyl]amino](carboxy)methyl]-5,5-dimethyl-1,3-thiazolidine-4-carboxylic acid
-
 ?
3.5.2.6 amoxicillin + H2O
-
 Salmonella sp. (2R,4S)-2-[(R)-[[(2R)-2-amino-2-(4-hydroxyphenyl)acetyl]amino](carboxy)methyl]-5,5-dimethyl-1,3-thiazolidine-4-carboxylic acid
-
 ?
3.5.2.6 ampicillin + H2O
-
 Escherichia coli (2R,4S)-2-[(R)-[[(2R)-2-amino-2-phenylacetyl]amino](carboxy)methyl]-5,5-dimethyl-1,3-thiazolidine-4-carboxylic acid
-
 ?
3.5.2.6 ampicillin + H2O
-
 Klebsiella pneumoniae (2R,4S)-2-[(R)-[[(2R)-2-amino-2-phenylacetyl]amino](carboxy)methyl]-5,5-dimethyl-1,3-thiazolidine-4-carboxylic acid
-
 ?
3.5.2.6 ampicillin + H2O
-
 Salmonella sp. (2R,4S)-2-[(R)-[[(2R)-2-amino-2-phenylacetyl]amino](carboxy)methyl]-5,5-dimethyl-1,3-thiazolidine-4-carboxylic acid
-
 ?
3.5.2.6 cefotaxime + H2O
-
 Escherichia coli (2R)-5-[(acetyloxy)methyl]-2-[(R)-[[(2E)-2-(2-amino-1,3-thiazol-4-yl)-2-(methoxyimino)acetyl]amino](carboxy)methyl]-3,6-dihydro-2H-1,3-thiazine-4-carboxylic acid
-
 ?
3.5.2.6 cefotaxime + H2O
-
 Klebsiella pneumoniae (2R)-5-[(acetyloxy)methyl]-2-[(R)-[[(2E)-2-(2-amino-1,3-thiazol-4-yl)-2-(methoxyimino)acetyl]amino](carboxy)methyl]-3,6-dihydro-2H-1,3-thiazine-4-carboxylic acid
-
 ?
3.5.2.6 cefotaxime + H2O
-
 Salmonella sp. (2R)-5-[(acetyloxy)methyl]-2-[(R)-[[(2E)-2-(2-amino-1,3-thiazol-4-yl)-2-(methoxyimino)acetyl]amino](carboxy)methyl]-3,6-dihydro-2H-1,3-thiazine-4-carboxylic acid
-
 ?
3.5.2.6 ceftazidime + H2O
-
 Escherichia coli ?
-
 ?
3.5.2.6 ceftazidime + H2O
-
 Klebsiella pneumoniae ?
-
 ?
3.5.2.6 ceftazidime + H2O
-
 Salmonella sp. ?
-
 ?
3.5.2.6 ceftriaxone + H2O
-
 Escherichia coli ?
-
 ?
3.5.2.6 ceftriaxone + H2O
-
 Klebsiella pneumoniae ?
-
 ?
3.5.2.6 ceftriaxone + H2O
-
 Salmonella sp. ?
-
 ?

Synonyms

EC Number Synonyms Comment Organism
3.5.2.6 BLA
-
 Escherichia coli

General Information

EC Number General Information Comment Organism
3.5.2.6 evolution genotyping and phenotyping of Escherichia coli strains with beta-lactamase activity in faeces from ducks, phylogenetic analysis. 5 (38.46%) Salmonella isolates are found to harbour gene blaCTX-M. Six Samonella isolates (46.15%) are detected as AmpC producers possessing gene blaAmpC. Significantly higher occurrence of beta-lactamase and biofilm producing Enterobacteriaceae isolates is detected in backyard ducks than organized farms Salmonella sp.
3.5.2.6 evolution genotyping and phenotyping of Escherichia coli strains with beta-lactamase activity in faeces from ducks, phylogenetic analysis. Among the 87 phenotypically beta-lactamase producing Escherichia coli, 19 (17.43%), 6 (5.05%) and 15 (13.76%) isolates possess genes blaTEM, blaSHV, and blaCTX-M genes, respectively. Beta-lactamase producing Escherichia coli isolates belong to 14 different serogroups such as O1, O2, O3, O5, O7, O8, O35, O83, O84, O88, O119, O128, O145 and O157. 87 Escherichia coli isolates (79.82%) are detected as AmpC producers possessing gene blaAmpC. Significantly higher occurrence of beta-lactamase and biofilm producing Enterobacteriaceae isolates is detected in backyard ducks than organized farms Escherichia coli
3.5.2.6 evolution genotyping and phenotyping of Escherichia coli strains with beta-lactamase activity in faeces from ducks, phylogenetic analysis. In Klebsiella pneumoniae 10, 3, and 4 isolates possess blaTEM, blaSHV, and blaCTX-M genes, respectively. The sequences of selected PCR products are found 98% cognate with blaCTX-M-9, blaSHV-12 and blaTEM-1. 13 Klebsiella pneumoniae isolates (43.33%) are detected as AmpC producers possessing gene blaAmpC. Significantly higher occurrence of beta-lactamase and biofilm producing Enterobacteriaceae isolates is detected in backyard ducks than organized farms Klebsiella pneumoniae
3.5.2.6 additional information consumption of antibiotic through feed or during therapy is considered as potential reason for generation of antimicrobial resistant bacteria in birds Escherichia coli
3.5.2.6 additional information consumption of antibiotic through feed or during therapy is considered as potential reason for generation of antimicrobial resistant bacteria in birds Klebsiella pneumoniae
3.5.2.6 additional information consumption of antibiotic through feed or during therapy is considered as potential reason for generation of antimicrobial resistant bacteria in birds Salmonella sp.