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Literature summary extracted from

  • Xun, L.; Webster, C.M.
    A monooxygenase catalyzes sequential dechlorinations of 2,4,6-trichlorophenol by oxidative and hydrolytic reactions (2004), J. Biol. Chem., 279, 6696-6700 .
    View publication on PubMed

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
1.14.14.173 2,4,6-trichlorophenol + FADH2 + O2 Cupriavidus necator
-
 2,6-dichloro-1,4-benzoquinone + Cl- + FAD + H2O
-
 ?
1.14.14.173 2,4,6-trichlorophenol + FADH2 + O2 Cupriavidus necator JMP134
-
 2,6-dichloro-1,4-benzoquinone + Cl- + FAD + H2O
-
 ?
1.14.14.173 2,6-dichlorohydroquinone + FADH2 + O2 Cupriavidus necator
-
 2-chloro-6-hydroxy-1,4-benzoquinone + Cl- + FAD + H2O
-
 ?
1.14.14.173 2,6-dichlorohydroquinone + FADH2 + O2 Cupriavidus necator JMP134
-
 2-chloro-6-hydroxy-1,4-benzoquinone + Cl- + FAD + H2O
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
1.14.14.173 Cupriavidus necator
-
-
-
1.14.14.173 Cupriavidus necator JMP134
-
-
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
1.14.14.173 2,4,6-trichlorophenol + FADH2 + O2
-
 Cupriavidus necator 2,6-dichloro-1,4-benzoquinone + Cl- + FAD + H2O
-
 ?
1.14.14.173 2,4,6-trichlorophenol + FADH2 + O2
-
 Cupriavidus necator JMP134 2,6-dichloro-1,4-benzoquinone + Cl- + FAD + H2O
-
 ?
1.14.14.173 2,6-dichlorohydroquinone + FADH2 + O2
-
 Cupriavidus necator 2-chloro-6-hydroxy-1,4-benzoquinone + Cl- + FAD + H2O
-
 ?
1.14.14.173 2,6-dichlorohydroquinone + FADH2 + O2
-
 Cupriavidus necator JMP134 2-chloro-6-hydroxy-1,4-benzoquinone + Cl- + FAD + H2O
-
 ?
1.14.14.173 2,6-dichlorophenol + FADH2 + O2
-
 Cupriavidus necator 2,6-dichlorohydroquinone + FAD + H2O
-
 ?
1.14.14.173 2,6-dichlorophenol + FADH2 + O2
-
 Cupriavidus necator JMP134 2,6-dichlorohydroquinone + FAD + H2O
-
 ?

Synonyms

EC Number Synonyms Comment Organism
1.14.14.173 2,4,6-TCP 4-monooxygenase
-
 Cupriavidus necator
1.14.14.173 2,4,6-trichlorophenol 4-monooxygenase
-
 Cupriavidus necator
1.14.14.173 tcpA
-
 Cupriavidus necator

Cofactor

EC Number Cofactor Comment Organism Structure
1.14.14.173 FADH2
-
 Cupriavidus necator
1.14.14.173 NADH
-
 Cupriavidus necator