EC Number | Cloned (Comment) | Organism |
---|---|---|
1.14.14.172 | expressed in Escherichia coli DH10B cells | Ralstonia sp. T6 |
EC Number | Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|---|
1.14.14.172 | 3,5,6-trichloropyridin-2-ol + FADH2 + O2 | Ralstonia sp. T6 | - |
3,6-dichloropyridine-2,5-dione + Cl- + FAD + H2O | - |
? | |
1.14.14.172 | 3,6-dichloropyridine-2,5-diol + FADH2 + O2 | Ralstonia sp. T6 | - |
6-chloro-3-hydroxypyridine-2,5-dione + Cl- + FAD + H2O | - |
? | |
1.14.14.172 | 6-chloropyridine-2,3,5-triol + FADH2 + O2 | Ralstonia sp. T6 | - |
3,6-dihydroxypyridine-2,5-dione + Cl- + FAD + H2O | - |
? |
EC Number | Organism | UniProt | Comment | Textmining |
---|---|---|---|---|
1.14.14.172 | Ralstonia sp. T6 | L7VFL7 | - |
- |
EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|---|
1.14.14.172 | 3,5,6-trichloropyridin-2-ol + FADH2 + O2 | - |
Ralstonia sp. T6 | 3,6-dichloropyridine-2,5-dione + Cl- + FAD + H2O | - |
? | |
1.14.14.172 | 3,6-dichloropyridine-2,5-diol + FADH2 + O2 | - |
Ralstonia sp. T6 | 6-chloro-3-hydroxypyridine-2,5-dione + Cl- + FAD + H2O | - |
? | |
1.14.14.172 | 6-chloropyridine-2,3,5-triol + FADH2 + O2 | - |
Ralstonia sp. T6 | 3,6-dihydroxypyridine-2,5-dione + Cl- + FAD + H2O | - |
? |
EC Number | Synonyms | Comment | Organism |
---|---|---|---|
1.14.14.172 | tcpA | - |
Ralstonia sp. T6 |
EC Number | Cofactor | Comment | Organism | Structure |
---|---|---|---|---|
1.14.14.172 | FADH2 | the enzyme needs flavin reductase TcpX to supply FADH2 when transforming 3,5,6-trichloropyridin-2-ol | Ralstonia sp. T6 |
EC Number | General Information | Comment | Organism |
---|---|---|---|
1.14.14.172 | malfunction | an enzyme gene disruption mutant is not able to degrade 3,5,6-trichloropyridin-2-ol but 3,6-dihydroxypyridine-2,5-dione | Ralstonia sp. T6 |
1.14.14.172 | metabolism | key enzyme in the initial step of 3,5,6-trichloropyridin-2-ol degradation | Ralstonia sp. T6 |