Literature summary extracted from

Ferrao, P.M.; dAvila-Levy, C.M.; Araujo-Jorge, T.C.; Degrave, W.M.; Goncalves, A.d.a. .S.; Garzoni, L.R.; Lima, A.P.; Feige, J.J.; Bailly, S.; Mendonca-Lima, L.; Waghabi, M.C.
Cruzipain activates latent TGF-beta from host cells during T. cruzi invasion (2015), PLoS ONE, 10, e0124832 .

Application

EC Number	Application	Comment	Organism
3.4.22.51	medicine	cruzipain inhibition is a chemotherapeutic approach for Chagas disease because of its trypanocidal activity and due to the inhibitory effect on TGF-beta activation	Trypanosoma cruzi

Localization

EC Number	Localization	Comment	Organism	GeneOntology No.	Textmining

Organism

EC Number	Organism	UniProt	Comment	Textmining
3.4.22.51	Trypanosoma cruzi	P25779	-	-

Source Tissue

EC Number	Source Tissue	Comment	Organism	Textmining
3.4.22.51	epimastigote	-	Trypanosoma cruzi	-

Use of this online version of BRENDA is free under the CC BY 4.0 license. See terms of use for full details.

Release 2023.1 (January 2023)