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Literature summary extracted from

  • Cipressa, F.; Morciano, P.; Bosso, G.; Mannini, L.; Galati, A.; Raffa, G.D.; Cacchione, S.; Musio, A.; Cenci, G.
    A role for Separase in telomere protection (2016), Nat. Commun., 7, 10405 .
    View publication on PubMedView publication on EuropePMC

Localization

EC Number Localization Comment Organism GeneOntology No. Textmining
3.4.22.49 additional information separase binds terminin proteins and HP1, and that it is enriched at telomeres Drosophila sp. (in: flies)
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Organism

EC Number Organism UniProt Comment Textmining
3.4.22.49 Drosophila sp. (in: flies)
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General Information

EC Number General Information Comment Organism
3.4.22.49 malfunction mutations in the Drosophila Separase encoding gene Sse lead not only to endoreduplication but also telomeric fusions, suggesting a role for Sse in telomere capping Drosophila sp. (in: flies)
3.4.22.49 physiological function Separase plays an evolutionarily conserved role in telomere protection Drosophila sp. (in: flies)