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Literature summary extracted from

  • Akparov, V.; Timofeev, V.; Khaliullin, I.; Svedas, V.; Kuranova, I.
    Structure of the carboxypeptidase B complex with N-sulfamoyl-L-phenylalanine - a transition state analog of non-specific substrate (2018), J. Biomol. Struct. Dyn., 36, 956-965 .
    View publication on PubMed

Application

EC Number Application Comment Organism
3.4.17.2 pharmacology carboxypeptidase B is commonly used in the industrial insulin production and as a template for drug design Sus scrofa

Crystallization (Commentary)

EC Number Crystallization (Comment) Organism
3.4.17.2 structure of the complex of the enzyme with a transition state analog N-sulfamoyl-L-phenylalanine solved at 1.74 A. Crystals of the enzyme/N-sulfamoyl-L-phenylalanine complex are grown in a capillary in microgravity using the counter-diffusion technique Sus scrofa

Organism

EC Number Organism UniProt Comment Textmining
3.4.17.2 Sus scrofa P09955
-
-

Source Tissue

EC Number Source Tissue Comment Organism Textmining
3.4.17.2 pancreas
-
 Sus scrofa
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
3.4.17.2 additional information Ser207, Gly253, Tyr248, and Asp255 residues play major role in the substrate recognition by S1-subsite Sus scrofa ?
-
 ?

Synonyms

EC Number Synonyms Comment Organism
3.4.17.2 CPB
-
 Sus scrofa