EC Number | Activating Compound | Comment | Organism | Structure |
---|---|---|---|---|
3.4.21.36 | Trypsin | - |
Homo sapiens | |
3.4.21.36 | Trypsin | - |
Sus scrofa |
EC Number | Cloned (Comment) | Organism |
---|---|---|
3.4.21.36 | expressed in HEK-293T cells | Homo sapiens |
EC Number | Inhibitors | Comment | Organism | Structure |
---|---|---|---|---|
3.4.21.36 | Schistocerca gregaria proteinase inhibitor 2 variant E1 | Tyr-Cys-Thr-Leu-Met-Leu-Cys-His | Homo sapiens | |
3.4.21.36 | Schistocerca gregaria proteinase inhibitor 2 variant E1 | Tyr-Cys-Thr-Leu-Met-Leu-Cys-His | Sus scrofa | |
3.4.21.36 | Schistocerca gregaria proteinase inhibitor 2 variant E10 | Ala-Cys-Thr-Leu-Met-Leu-Cys-His | Homo sapiens | |
3.4.21.36 | Schistocerca gregaria proteinase inhibitor 2 variant E10 | Ala-Cys-Thr-Leu-Met-Leu-Cys-His | Sus scrofa | |
3.4.21.36 | Schistocerca gregaria proteinase inhibitor 2 variant E11 | Ala-Cys-Thr-Leu-Met-Tyr-Cys-His | Homo sapiens | |
3.4.21.36 | Schistocerca gregaria proteinase inhibitor 2 variant E11 | Ala-Cys-Thr-Leu-Met-Tyr-Cys-His | Sus scrofa | |
3.4.21.36 | Schistocerca gregaria proteinase inhibitor 2 variant E12 | Tyr-Cys-Thr-Leu-Met-Leu-Cys-Ala | Homo sapiens | |
3.4.21.36 | Schistocerca gregaria proteinase inhibitor 2 variant E12 | Tyr-Cys-Thr-Leu-Met-Leu-Cys-Ala | Sus scrofa | |
3.4.21.36 | Schistocerca gregaria proteinase inhibitor 2 variant E2 | Tyr-Cys-Thr-Ile-Met-Leu-Cys-His | Homo sapiens | |
3.4.21.36 | Schistocerca gregaria proteinase inhibitor 2 variant E2 | Tyr-Cys-Thr-Ile-Met-Leu-Cys-His | Sus scrofa | |
3.4.21.36 | Schistocerca gregaria proteinase inhibitor 2 variant E3 | Tyr-Cys-Thr-Val-Met-Leu-Cys-His | Homo sapiens | |
3.4.21.36 | Schistocerca gregaria proteinase inhibitor 2 variant E3 | Tyr-Cys-Thr-Val-Met-Leu-Cys-His | Sus scrofa | |
3.4.21.36 | Schistocerca gregaria proteinase inhibitor 2 variant E4 | Tyr-Cys-Thr-Met-Met-Leu-Cys-His | Homo sapiens | |
3.4.21.36 | Schistocerca gregaria proteinase inhibitor 2 variant E4 | Tyr-Cys-Thr-Met-Met-Leu-Cys-His | Sus scrofa | |
3.4.21.36 | Schistocerca gregaria proteinase inhibitor 2 variant E5 | Tyr-Cys-Thr-Ala-Met-Leu-Cys-His | Homo sapiens | |
3.4.21.36 | Schistocerca gregaria proteinase inhibitor 2 variant E5 | Tyr-Cys-Thr-Ala-Met-Leu-Cys-His | Sus scrofa | |
3.4.21.36 | Schistocerca gregaria proteinase inhibitor 2 variant E6 | Tyr-Cys-Thr-Ser-Met-Leu-Cys-His | Homo sapiens | |
3.4.21.36 | Schistocerca gregaria proteinase inhibitor 2 variant E6 | Tyr-Cys-Thr-Ser-Met-Leu-Cys-His | Sus scrofa | |
3.4.21.36 | Schistocerca gregaria proteinase inhibitor 2 variant E7 | Tyr-Cys-Thr-Ile-Met-Glu-Cys-His | Homo sapiens | |
3.4.21.36 | Schistocerca gregaria proteinase inhibitor 2 variant E7 | Tyr-Cys-Thr-Ile-Met-Glu-Cys-His | Sus scrofa | |
3.4.21.36 | Schistocerca gregaria proteinase inhibitor 2 variant E8 | Tyr-Cys-Thr-Leu-Arg-Leu-Cys-His | Homo sapiens | |
3.4.21.36 | Schistocerca gregaria proteinase inhibitor 2 variant E8 | Tyr-Cys-Thr-Leu-Arg-Leu-Cys-His | Sus scrofa | |
3.4.21.36 | Schistocerca gregaria proteinase inhibitor 2 variant E9 | Tyr-Cys-Thr-Leu-Met-Tyr-Cys-His | Homo sapiens | |
3.4.21.36 | Schistocerca gregaria proteinase inhibitor 2 variant E9 | Tyr-Cys-Thr-Leu-Met-Tyr-Cys-His | Sus scrofa |
EC Number | KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|---|
3.4.21.36 | 0.166 | - |
succinyl-L-Ala-L-Ala-L-Pro-L-Ala-4-nitroanilide | isoform CELA1, at pH 8.0 and 22°C | Sus scrofa | |
3.4.21.36 | 0.259 | - |
succinyl-L-Ala-L-Ala-L-Pro-L-Leu-4-nitroanilide | isoform CELA3B, at pH 8.0 and 22°C | Homo sapiens | |
3.4.21.36 | 0.288 | - |
succinyl-L-Ala-L-Ala-L-Pro-L-Met-4-nitroanilide | isoform CELA3B, at pH 8.0 and 22°C | Homo sapiens | |
3.4.21.36 | 0.374 | - |
succinyl-L-Ala-L-Ala-L-Pro-L-Ala-4-nitroanilide | isoform CELA3B, at pH 8.0 and 22°C | Homo sapiens | |
3.4.21.36 | 0.43 | - |
succinyl-L-Ala-L-Ala-L-Pro-L-Val-4-nitroanilide | isoform CELA3B, at pH 8.0 and 22°C | Homo sapiens | |
3.4.21.36 | 0.452 | - |
succinyl-L-Ala-L-Ala-L-Pro-L-Met-4-nitroanilide | isoform CELA3A, at pH 8.0 and 22°C | Homo sapiens | |
3.4.21.36 | 0.484 | - |
succinyl-L-Ala-L-Ala-L-Pro-L-Ile-4-nitroanilide | isoform CELA3B, at pH 8.0 and 22°C | Homo sapiens | |
3.4.21.36 | 0.54 | - |
succinyl-L-Ala-L-Ala-L-Pro-L-Met-4-nitroanilide | isoform CELA1, at pH 8.0 and 22°C | Sus scrofa | |
3.4.21.36 | 0.722 | - |
succinyl-L-Ala-L-Ala-L-Pro-L-Leu-4-nitroanilide | isoform CELA3A, at pH 8.0 and 22°C | Homo sapiens | |
3.4.21.36 | 0.785 | - |
succinyl-L-Ala-L-Ala-L-Pro-L-Leu-4-nitroanilide | isoform CELA1, at pH 8.0 and 22°C | Sus scrofa | |
3.4.21.36 | 0.984 | - |
succinyl-L-Ala-L-Ala-L-Pro-L-Ser-4-nitroanilide | isoform CELA3B, at pH 8.0 and 22°C | Homo sapiens | |
3.4.21.36 | 0.995 | - |
succinyl-L-Ala-L-Ala-L-Pro-L-Ile-4-nitroanilide | isoform CELA1, at pH 8.0 and 22°C | Sus scrofa | |
3.4.21.36 | 1.029 | - |
succinyl-L-Ala-L-Ala-L-Pro-L-Val-4-nitroanilide | isoform CELA1, at pH 8.0 and 22°C | Sus scrofa | |
3.4.21.36 | 1.06 | - |
succinyl-L-Ala-L-Ala-L-Pro-L-Ile-4-nitroanilide | isoform CELA3A, at pH 8.0 and 22°C | Homo sapiens | |
3.4.21.36 | 1.089 | - |
succinyl-L-Ala-L-Ala-L-Pro-L-Ala-4-nitroanilide | isoform CELA3A, at pH 8.0 and 22°C | Homo sapiens | |
3.4.21.36 | 1.178 | - |
succinyl-L-Ala-L-Ala-L-Pro-L-Val-4-nitroanilide | isoform CELA3A, at pH 8.0 and 22°C | Homo sapiens | |
3.4.21.36 | 1.447 | - |
succinyl-L-Ala-L-Ala-L-Pro-L-Ser-4-nitroanilide | isoform CELA3A, at pH 8.0 and 22°C | Homo sapiens | |
3.4.21.36 | 1.555 | - |
succinyl-L-Ala-L-Ala-L-Pro-Gly-4-nitroanilide | isoform CELA1, at pH 8.0 and 22°C | Sus scrofa | |
3.4.21.36 | 2.311 | - |
succinyl-L-Ala-L-Ala-L-Pro-L-Ser-4-nitroanilide | isoform CELA1, at pH 8.0 and 22°C | Sus scrofa |
EC Number | Organism | UniProt | Comment | Textmining |
---|---|---|---|---|
3.4.21.36 | Homo sapiens | - |
- |
- |
3.4.21.36 | Sus scrofa | - |
- |
- |
EC Number | Purification (Comment) | Organism |
---|---|---|
3.4.21.36 | nickel-affinity chromatography | Homo sapiens |
EC Number | Source Tissue | Comment | Organism | Textmining |
---|---|---|---|---|
3.4.21.36 | pancreas | - |
Homo sapiens | - |
3.4.21.36 | pancreas | - |
Sus scrofa | - |
EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|---|
3.4.21.36 | succinyl-L-Ala-L-Ala-L-Pro-Gly-4-nitroanilide + H2O | - |
Homo sapiens | ? | - |
? | |
3.4.21.36 | succinyl-L-Ala-L-Ala-L-Pro-Gly-4-nitroanilide + H2O | - |
Sus scrofa | ? | - |
? | |
3.4.21.36 | succinyl-L-Ala-L-Ala-L-Pro-L-Ala-4-nitroanilide + H2O | - |
Homo sapiens | ? | - |
? | |
3.4.21.36 | succinyl-L-Ala-L-Ala-L-Pro-L-Ala-4-nitroanilide + H2O | - |
Sus scrofa | ? | - |
? | |
3.4.21.36 | succinyl-L-Ala-L-Ala-L-Pro-L-Ile-4-nitroanilide + H2O | - |
Homo sapiens | ? | - |
? | |
3.4.21.36 | succinyl-L-Ala-L-Ala-L-Pro-L-Ile-4-nitroanilide + H2O | - |
Sus scrofa | ? | - |
? | |
3.4.21.36 | succinyl-L-Ala-L-Ala-L-Pro-L-Leu-4-nitroanilide + H2O | - |
Homo sapiens | ? | - |
? | |
3.4.21.36 | succinyl-L-Ala-L-Ala-L-Pro-L-Leu-4-nitroanilide + H2O | - |
Sus scrofa | ? | - |
? | |
3.4.21.36 | succinyl-L-Ala-L-Ala-L-Pro-L-Met-4-nitroanilide + H2O | - |
Homo sapiens | ? | - |
? | |
3.4.21.36 | succinyl-L-Ala-L-Ala-L-Pro-L-Met-4-nitroanilide + H2O | - |
Sus scrofa | ? | - |
? | |
3.4.21.36 | succinyl-L-Ala-L-Ala-L-Pro-L-Ser-4-nitroanilide + H2O | - |
Homo sapiens | ? | - |
? | |
3.4.21.36 | succinyl-L-Ala-L-Ala-L-Pro-L-Ser-4-nitroanilide + H2O | - |
Sus scrofa | ? | - |
? | |
3.4.21.36 | succinyl-L-Ala-L-Ala-L-Pro-L-Val-4-nitroanilide + H2O | - |
Homo sapiens | ? | - |
? | |
3.4.21.36 | succinyl-L-Ala-L-Ala-L-Pro-L-Val-4-nitroanilide + H2O | - |
Sus scrofa | ? | - |
? |
EC Number | Synonyms | Comment | Organism |
---|---|---|---|
3.4.21.36 | CELA1 | - |
Sus scrofa |
3.4.21.36 | CELA3A | isoform | Homo sapiens |
3.4.21.36 | CELA3B | isoform | Homo sapiens |
3.4.21.36 | chymotrypsin-like elastase | - |
Homo sapiens |
3.4.21.36 | chymotrypsin-like elastase | - |
Sus scrofa |
3.4.21.36 | elastase 1 | - |
Sus scrofa |
3.4.21.36 | pancreatic elastase 3 | - |
Homo sapiens |
EC Number | Turnover Number Minimum [1/s] | Turnover Number Maximum [1/s] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|---|
3.4.21.36 | 0.14 | - |
succinyl-L-Ala-L-Ala-L-Pro-L-Ser-4-nitroanilide | isoform CELA3A, at pH 8.0 and 22°C | Homo sapiens | |
3.4.21.36 | 0.24 | - |
succinyl-L-Ala-L-Ala-L-Pro-L-Met-4-nitroanilide | isoform CELA3A, at pH 8.0 and 22°C | Homo sapiens | |
3.4.21.36 | 0.24 | - |
succinyl-L-Ala-L-Ala-L-Pro-L-Met-4-nitroanilide | isoform CELA3B, at pH 8.0 and 22°C | Homo sapiens | |
3.4.21.36 | 0.26 | - |
succinyl-L-Ala-L-Ala-L-Pro-L-Ser-4-nitroanilide | isoform CELA3B, at pH 8.0 and 22°C | Homo sapiens | |
3.4.21.36 | 0.7 | - |
succinyl-L-Ala-L-Ala-L-Pro-L-Met-4-nitroanilide | isoform CELA1, at pH 8.0 and 22°C | Sus scrofa | |
3.4.21.36 | 0.99 | - |
succinyl-L-Ala-L-Ala-L-Pro-L-Ile-4-nitroanilide | isoform CELA3A, at pH 8.0 and 22°C | Homo sapiens | |
3.4.21.36 | 1.01 | - |
succinyl-L-Ala-L-Ala-L-Pro-L-Leu-4-nitroanilide | isoform CELA3B, at pH 8.0 and 22°C | Homo sapiens | |
3.4.21.36 | 1.16 | - |
succinyl-L-Ala-L-Ala-L-Pro-L-Leu-4-nitroanilide | isoform CELA3A, at pH 8.0 and 22°C | Homo sapiens | |
3.4.21.36 | 1.25 | - |
succinyl-L-Ala-L-Ala-L-Pro-L-Ile-4-nitroanilide | isoform CELA3B, at pH 8.0 and 22°C | Homo sapiens | |
3.4.21.36 | 1.86 | - |
succinyl-L-Ala-L-Ala-L-Pro-Gly-4-nitroanilide | isoform CELA1, at pH 8.0 and 22°C | Sus scrofa | |
3.4.21.36 | 2.44 | - |
succinyl-L-Ala-L-Ala-L-Pro-L-Val-4-nitroanilide | isoform CELA3A, at pH 8.0 and 22°C | Homo sapiens | |
3.4.21.36 | 2.87 | - |
succinyl-L-Ala-L-Ala-L-Pro-L-Ile-4-nitroanilide | isoform CELA1, at pH 8.0 and 22°C | Sus scrofa | |
3.4.21.36 | 3.66 | - |
succinyl-L-Ala-L-Ala-L-Pro-L-Val-4-nitroanilide | isoform CELA3B, at pH 8.0 and 22°C | Homo sapiens | |
3.4.21.36 | 5.62 | - |
succinyl-L-Ala-L-Ala-L-Pro-L-Ser-4-nitroanilide | isoform CELA1, at pH 8.0 and 22°C | Sus scrofa | |
3.4.21.36 | 16.9 | - |
succinyl-L-Ala-L-Ala-L-Pro-L-Val-4-nitroanilide | isoform CELA1, at pH 8.0 and 22°C | Sus scrofa | |
3.4.21.36 | 22.9 | - |
succinyl-L-Ala-L-Ala-L-Pro-L-Ala-4-nitroanilide | isoform CELA3A, at pH 8.0 and 22°C | Homo sapiens | |
3.4.21.36 | 24.8 | - |
succinyl-L-Ala-L-Ala-L-Pro-L-Ala-4-nitroanilide | isoform CELA3B, at pH 8.0 and 22°C | Homo sapiens | |
3.4.21.36 | 57.8 | - |
succinyl-L-Ala-L-Ala-L-Pro-L-Leu-4-nitroanilide | isoform CELA1, at pH 8.0 and 22°C | Sus scrofa | |
3.4.21.36 | 115 | - |
succinyl-L-Ala-L-Ala-L-Pro-L-Ala-4-nitroanilide | isoform CELA1, at pH 8.0 and 22°C | Sus scrofa |
EC Number | kcat/KM Value [1/mMs-1] | kcat/KM Value Maximum [1/mMs-1] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|---|
3.4.21.36 | 0.099 | - |
succinyl-L-Ala-L-Ala-L-Pro-L-Ser-4-nitroanilide | isoform CELA3A, at pH 8.0 and 22°C | Homo sapiens | |
3.4.21.36 | 0.26 | - |
succinyl-L-Ala-L-Ala-L-Pro-L-Ser-4-nitroanilide | isoform CELA3B, at pH 8.0 and 22°C | Homo sapiens | |
3.4.21.36 | 0.53 | - |
succinyl-L-Ala-L-Ala-L-Pro-L-Met-4-nitroanilide | isoform CELA3A, at pH 8.0 and 22°C | Homo sapiens | |
3.4.21.36 | 0.83 | - |
succinyl-L-Ala-L-Ala-L-Pro-L-Met-4-nitroanilide | isoform CELA3B, at pH 8.0 and 22°C | Homo sapiens | |
3.4.21.36 | 0.93 | - |
succinyl-L-Ala-L-Ala-L-Pro-L-Ile-4-nitroanilide | isoform CELA3A, at pH 8.0 and 22°C | Homo sapiens | |
3.4.21.36 | 1.2 | - |
succinyl-L-Ala-L-Ala-L-Pro-Gly-4-nitroanilide | isoform CELA1, at pH 8.0 and 22°C | Sus scrofa | |
3.4.21.36 | 1.3 | - |
succinyl-L-Ala-L-Ala-L-Pro-L-Met-4-nitroanilide | isoform CELA1, at pH 8.0 and 22°C | Sus scrofa | |
3.4.21.36 | 1.6 | - |
succinyl-L-Ala-L-Ala-L-Pro-L-Leu-4-nitroanilide | isoform CELA3A, at pH 8.0 and 22°C | Homo sapiens | |
3.4.21.36 | 2.1 | - |
succinyl-L-Ala-L-Ala-L-Pro-L-Val-4-nitroanilide | isoform CELA3A, at pH 8.0 and 22°C | Homo sapiens | |
3.4.21.36 | 2.4 | - |
succinyl-L-Ala-L-Ala-L-Pro-L-Ser-4-nitroanilide | isoform CELA1, at pH 8.0 and 22°C | Sus scrofa | |
3.4.21.36 | 2.6 | - |
succinyl-L-Ala-L-Ala-L-Pro-L-Ile-4-nitroanilide | isoform CELA3B, at pH 8.0 and 22°C | Homo sapiens | |
3.4.21.36 | 2.9 | - |
succinyl-L-Ala-L-Ala-L-Pro-L-Ile-4-nitroanilide | isoform CELA1, at pH 8.0 and 22°C | Sus scrofa | |
3.4.21.36 | 3.9 | - |
succinyl-L-Ala-L-Ala-L-Pro-L-Leu-4-nitroanilide | isoform CELA3B, at pH 8.0 and 22°C | Homo sapiens | |
3.4.21.36 | 8.5 | - |
succinyl-L-Ala-L-Ala-L-Pro-L-Val-4-nitroanilide | isoform CELA3B, at pH 8.0 and 22°C | Homo sapiens | |
3.4.21.36 | 17 | - |
succinyl-L-Ala-L-Ala-L-Pro-L-Val-4-nitroanilide | isoform CELA1, at pH 8.0 and 22°C | Sus scrofa | |
3.4.21.36 | 21 | - |
succinyl-L-Ala-L-Ala-L-Pro-L-Ala-4-nitroanilide | isoform CELA3A, at pH 8.0 and 22°C | Homo sapiens | |
3.4.21.36 | 66 | - |
succinyl-L-Ala-L-Ala-L-Pro-L-Ala-4-nitroanilide | isoform CELA3B, at pH 8.0 and 22°C | Homo sapiens | |
3.4.21.36 | 74 | - |
succinyl-L-Ala-L-Ala-L-Pro-L-Leu-4-nitroanilide | isoform CELA1, at pH 8.0 and 22°C | Sus scrofa | |
3.4.21.36 | 690 | - |
succinyl-L-Ala-L-Ala-L-Pro-L-Ala-4-nitroanilide | isoform CELA1, at pH 8.0 and 22°C | Sus scrofa |