EC Number | Cloned (Comment) | Organism |
---|---|---|
3.4.22.15 | real-time PCR enzyme expression analysis, enzyme in vitro translation | Helicoverpa armigera |
EC Number | Inhibitors | Comment | Organism | Structure |
---|---|---|---|---|
3.4.22.15 | CLIK148 | cathepsin L-specific inhibitor | Helicoverpa armigera | |
3.4.22.15 | E64d | - |
Helicoverpa armigera |
EC Number | Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|---|
3.4.22.15 | extracellular | - |
Helicoverpa armigera | - |
- |
EC Number | Organism | UniProt | Comment | Textmining |
---|---|---|---|---|
3.4.22.15 | Helicoverpa armigera | B9UCR2 | - |
- |
EC Number | Source Tissue | Comment | Organism | Textmining |
---|---|---|---|---|
3.4.22.15 | BCIRL-HZ-AM1 cell | - |
Helicoverpa armigera | - |
3.4.22.15 | epithelium | - |
Helicoverpa armigera | - |
3.4.22.15 | larva | expression pattern and proteolytic activity of Har-CatL in the larval midgut also during metamorphosis, immunohistochemic analysis, overview | Helicoverpa armigera | - |
3.4.22.15 | midgut | - |
Helicoverpa armigera | - |
3.4.22.15 | additional information | expression and activity of Helicoverpa armigera cathepsin L (Har-CatL) are high in the midgut at the mid-late stage of the 6th-instar larvae and are responsive to the upstream hormone ecdysone. Developmental changes in Helicoverpa armigera cathepsin L (CatL) mRNA and protein, proteolytic activity, overview | Helicoverpa armigera | - |
EC Number | Synonyms | Comment | Organism |
---|---|---|---|
3.4.22.15 | CathL | - |
Helicoverpa armigera |
3.4.22.15 | CatL | - |
Helicoverpa armigera |
3.4.22.15 | Har-CatL | - |
Helicoverpa armigera |
EC Number | Temperature Optimum [°C] | Temperature Optimum Maximum [°C] | Comment | Organism |
---|---|---|---|---|
3.4.22.15 | 37 | - |
assay at | Helicoverpa armigera |
EC Number | pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
---|---|---|---|---|
3.4.22.15 | 4.4 | - |
assay at | Helicoverpa armigera |
EC Number | Organism | Comment | Expression |
---|---|---|---|
3.4.22.15 | Helicoverpa armigera | Har-CatL can be upregulated by hormone 20-hydroxyecdysone | up |
EC Number | General Information | Comment | Organism |
---|---|---|---|
3.4.22.15 | physiological function | cathepsin L participates in the remodeling of the midgut through dissociation of midgut cells and activation of apoptosis via caspase-1. Har-CatL can cleave pro-caspase-1 into the mature peptide, caspase-1 activity is regulated by Har-CatL. Enzyme Har-CatL regulates the dissociation and apoptosis of the larval midgut epithelium for midgut remodeling. Har-CatL-like expression is involved in midgut metamorphosis via degradation of intracellular and extracellular proteins | Helicoverpa armigera |