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Literature summary extracted from

  • Pedrajas, J.R.; Padilla, C.A.; McDonagh, B.; Barcena, J.A.
    Glutaredoxin participates in the reduction of peroxides by the mitochondrial 1-CYS peroxiredoxin in Saccharomyces cerevisiae (2010), Antioxid. Redox Signal., 13, 249-258 .
    View publication on PubMed

Cloned(Commentary)

EC Number Cloned (Comment) Organism
1.11.1.25 expression in Escherichia coli Saccharomyces cerevisiae

Localization

EC Number Localization Comment Organism GeneOntology No. Textmining
1.11.1.25 mitochondrion
-
 Saccharomyces cerevisiae 5739
-

Organism

EC Number Organism UniProt Comment Textmining
1.11.1.25 Saccharomyces cerevisiae P34227
-
-
1.11.1.25 Saccharomyces cerevisiae ATCC 204508 P34227
-
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
1.11.1.25 glutaredoxin + H2O2
-
 Saccharomyces cerevisiae glutaredoxin disulfide + 2 H2O
-
 ?
1.11.1.25 glutaredoxin + H2O2
-
 Saccharomyces cerevisiae ATCC 204508 glutaredoxin disulfide + 2 H2O
-
 ?
1.11.1.25 glutaredoxin + tert-butyl hydroperoxide
-
 Saccharomyces cerevisiae glutaredoxin disulfide + H2O + tert-butyl alcohol
-
 ?
1.11.1.25 glutaredoxin + tert-butyl hydroperoxide
-
 Saccharomyces cerevisiae ATCC 204508 glutaredoxin disulfide + H2O + tert-butyl alcohol
-
 ?

Synonyms

EC Number Synonyms Comment Organism
1.11.1.25 glutaredoxin-dependent peroxidase
-
 Saccharomyces cerevisiae
1.11.1.25 Prx1
-
 Saccharomyces cerevisiae

Temperature Optimum [°C]

EC Number Temperature Optimum [°C] Temperature Optimum Maximum [°C] Comment Organism
1.11.1.25 30
-
 assay at Saccharomyces cerevisiae

pH Optimum

EC Number pH Optimum Minimum pH Optimum Maximum Comment Organism
1.11.1.25 8.5
-
-
 Saccharomyces cerevisiae

pH Range

EC Number pH Minimum pH Maximum Comment Organism
1.11.1.25 7.5 9.3 pH 7.5: about 50% of maximal activity, pH 9.3: about 55% of maximal activity, substrate: tert-butyl hydroperoxide Saccharomyces cerevisiae

General Information

EC Number General Information Comment Organism
1.11.1.25 physiological function reduction of peroxides by mitochondrial Prx1 is of importance to protect this organelle from oxidative stress Saccharomyces cerevisiae