EC Number | Activating Compound | Comment | Organism | Structure |
---|---|---|---|---|
3.1.21.B1 | proliferating cell nuclear antigen | activity is enhanced by addition of Proliferating Cell Nuclear Antigen (PCNA) in vitro. The physical interaction between the two proteins through a PIP-motif of EndoQ and the toroidal structure of PCNA are critical for the stimulation of the endonuclease activity | Pyrococcus furiosus | |
3.1.21.B1 | proliferating cell nuclear antigen | activity is enhanced by addition of Proliferating Cell Nuclear Antigen (PCNA) in vitro. The physical interaction between the two proteins through a PIP-motif of EndoQ and the toroidal structure of PCNA are critical for the stimulation of the endonuclease activity | Thermococcus kodakarensis |
EC Number | Organism | UniProt | Comment | Textmining |
---|---|---|---|---|
3.1.21.B1 | Pyrococcus furiosus | Q8U0N5 | - |
- |
3.1.21.B1 | Pyrococcus furiosus ATCC 43587 | Q8U0N5 | - |
- |
3.1.21.B1 | Thermococcus kodakarensis | Q5JI33 | - |
- |
EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|---|
3.1.21.B1 | DNA + H2O | the enzyme recognizes uracil, abasic site and xanthine, as well as hypoxanthine, and cuts the phosphodiester bond at their 5' sides | Pyrococcus furiosus | ? | - |
? | |
3.1.21.B1 | DNA + H2O | the enzyme recognizes uracil, abasic site and xanthine, as well as hypoxanthine, and cuts the phosphodiester bond at their 5' sides | Thermococcus kodakarensis | ? | - |
? | |
3.1.21.B1 | DNA + H2O | the enzyme recognizes uracil, abasic site and xanthine, as well as hypoxanthine, and cuts the phosphodiester bond at their 5' sides | Pyrococcus furiosus ATCC 43587 | ? | - |
? |
EC Number | Synonyms | Comment | Organism |
---|---|---|---|
3.1.21.B1 | EndoQ | - |
Pyrococcus furiosus |
3.1.21.B1 | EndoQ | - |
Thermococcus kodakarensis |