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Literature summary extracted from

  • Majumder, P.; Rudack, T.; Beck, F.; Danev, R.; Pfeifer, G.; Nagy, I.; Baumeister, W.
    Cryo-EM structures of the archaeal PAN-proteasome reveal an around-the-ring ATPase cycle (2019), Proc. Natl. Acad. Sci. USA, 116, 534-539 .
    View publication on PubMedView publication on EuropePMC

Cloned(Commentary)

EC Number Cloned (Comment) Organism
5.6.1.5 expressed in Escherichia coli BL21-CodonPlus (DE3)-RIL cells Archaeoglobus fulgidus

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
5.6.1.5 ATP + H2O + polypeptide Archaeoglobus fulgidus
-
 ADP + phosphate + unfolded polypeptide
-
 ?
5.6.1.5 ATP + H2O + polypeptide Archaeoglobus fulgidus ATCC 49558
-
 ADP + phosphate + unfolded polypeptide
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
5.6.1.5 Archaeoglobus fulgidus O28303
-
-
5.6.1.5 Archaeoglobus fulgidus ATCC 49558 O28303
-
-

Purification (Commentary)

EC Number Purification (Comment) Organism
5.6.1.5 His-tag purification resin chromatography, MonoQ column chromatography, and Superose 6 gel filtration Archaeoglobus fulgidus

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
5.6.1.5 ATP + H2O + polypeptide
-
 Archaeoglobus fulgidus ADP + phosphate + unfolded polypeptide
-
 ?
5.6.1.5 ATP + H2O + polypeptide
-
 Archaeoglobus fulgidus ATCC 49558 ADP + phosphate + unfolded polypeptide
-
 ?

Subunits

EC Number Subunits Comment Organism
5.6.1.5 hexamer single-particle cryoelectron microscopy Archaeoglobus fulgidus

Synonyms

EC Number Synonyms Comment Organism
5.6.1.5 AAA-ATPase
-
 Archaeoglobus fulgidus
5.6.1.5 PAN
-
 Archaeoglobus fulgidus
5.6.1.5 PAN-CP complex
-
 Archaeoglobus fulgidus
5.6.1.5 proteasome-activating nucleotidase
-
 Archaeoglobus fulgidus