EC Number | Cloned (Comment) | Organism |
---|---|---|
3.1.3.7 | exprerssion in Escherichia coli | Mycobacterium tuberculosis |
3.1.4.59 | expression in Escherichia coli | Mycobacterium tuberculosis |
EC Number | Protein Variants | Comment | Organism |
---|---|---|---|
3.1.3.7 | D130A/H131A | mutant fails to hydrolyze c-di-AMP | Mycobacterium tuberculosis |
3.1.4.59 | D130A/H131A | mutant fails to hydrolyze c-di-AMP | Mycobacterium tuberculosis |
EC Number | Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|---|
3.1.3.7 | soluble | - |
Mycobacterium tuberculosis | - |
- |
3.1.4.59 | soluble | - |
Mycobacterium tuberculosis | - |
- |
EC Number | Organism | UniProt | Comment | Textmining |
---|---|---|---|---|
3.1.3.7 | Mycobacterium tuberculosis | P71615 | bifunctional oligoribonuclease and PAP phosphatase, enzyme has a DHH/DHHA1 domein | - |
3.1.3.7 | Mycobacterium tuberculosis H37Rv | P71615 | bifunctional oligoribonuclease and PAP phosphatase, enzyme has a DHH/DHHA1 domein | - |
3.1.4.59 | Mycobacterium tuberculosis | P71615 | bifunctional oligoribonuclease and PAP phosphatase, cf. EC 3.1.3.7. Enzyme has a DHH/DHHA1 domain | - |
3.1.4.59 | Mycobacterium tuberculosis H37Rv | P71615 | bifunctional oligoribonuclease and PAP phosphatase, cf. EC 3.1.3.7. Enzyme has a DHH/DHHA1 domain | - |
EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|---|
3.1.3.7 | adenosine 3',5'-bisphosphate + H2O | - |
Mycobacterium tuberculosis | AMP + phosphate | - |
? | |
3.1.3.7 | adenosine 3',5'-bisphosphate + H2O | - |
Mycobacterium tuberculosis H37Rv | AMP + phosphate | - |
? | |
3.1.3.7 | additional information | enzyme has c-di-AMP specific phosphodiesterase activity. It hydrolyzes c-di-AMP to 5'-AMP in two steps. First, it linearizes c-di-AMP into pApA , reaction of EC 3.1.4.59, which is further hydrolyzed to 5'-AMP, reaction of EC 3.1.4.60 | Mycobacterium tuberculosis | ? | - |
? | |
3.1.3.7 | additional information | enzyme has c-di-AMP specific phosphodiesterase activity. It hydrolyzes c-di-AMP to 5'-AMP in two steps. First, it linearizes c-di-AMP into pApA , reaction of EC 3.1.4.59, which is further hydrolyzed to 5'-AMP, reaction of EC 3.1.4.60 | Mycobacterium tuberculosis H37Rv | ? | - |
? | |
3.1.4.59 | cyclic di-3',5'-adenylate + H2O | - |
Mycobacterium tuberculosis | 5'-O-phosphonoadenylyl-(3'->5')-adenosine | - |
? | |
3.1.4.59 | cyclic di-3',5'-adenylate + H2O | - |
Mycobacterium tuberculosis H37Rv | 5'-O-phosphonoadenylyl-(3'->5')-adenosine | - |
? | |
3.1.4.59 | additional information | enzyme has c-di-AMP specific phosphodiesterase activity. It hydrolyzes c-di-AMP to 5'-AMP in two steps. First, it linearizes c-di-AMP into pApA , reaction of EC 3.1.4.59, which is further hydrolyzed to 5'-AMP, reaction of EC 3.1.4.60 | Mycobacterium tuberculosis | ? | - |
? | |
3.1.4.59 | additional information | enzyme has c-di-AMP specific phosphodiesterase activity. It hydrolyzes c-di-AMP to 5'-AMP in two steps. First, it linearizes c-di-AMP into pApA , reaction of EC 3.1.4.59, which is further hydrolyzed to 5'-AMP, reaction of EC 3.1.4.60 | Mycobacterium tuberculosis H37Rv | ? | - |
? |
EC Number | Synonyms | Comment | Organism |
---|---|---|---|
3.1.3.7 | NrnA | - |
Mycobacterium tuberculosis |
3.1.3.7 | Rv2837c | - |
Mycobacterium tuberculosis |
3.1.4.59 | NrnA | - |
Mycobacterium tuberculosis |
3.1.4.59 | Rv2837c | - |
Mycobacterium tuberculosis |