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Literature summary extracted from

  • Labyntseva, R.; Yavorovska, V.; Bevza, O.; Drapaylo, A.; Kalchenko, V.; Kosterin, S.
    Thiacalix[4]arenes remove the inhibitory effects of Zn cations on the myosin ATPase activity (2018), Nanoscale Res. Lett., 13, 224 .
    View publication on PubMedView publication on EuropePMC

Inhibitors

EC Number Inhibitors Comment Organism Structure
5.6.1.8 Zn2+ about 60% residual activity at 5 mM Zn2+. Tetrahydroxythiacalix[4]arene-tetrasulfosphonate and tetrahydroxythiacalix[4]arene-tetraphosphonate restore myosin S1 ATPase activity to the control level in the presence of 5 mM Zn2+ Sus scrofa

KM Value [mM]

EC Number KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
5.6.1.8 0.38
-
 ATP in the presence of 5 mM Zn2+, at pH 7.2 and 37°C Sus scrofa
5.6.1.8 0.49
-
 ATP in the absence of Zn2+, at pH 7.2 and 37°C Sus scrofa

Metals/Ions

EC Number Metals/Ions Comment Organism Structure
5.6.1.8 additional information uterine myosin S1 ATPase activity does not depend on the concentration of Mg2+ in the presence of 5 mM Zn2+ Sus scrofa

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
5.6.1.8 ATP + H2O + myosin bound to actin filament at position n Sus scrofa
-
 ADP + phosphate + myosin bound to actin filament at position n+1
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
5.6.1.8 Sus scrofa
-
-
-

Source Tissue

EC Number Source Tissue Comment Organism Textmining
5.6.1.8 myometrium
-
 Sus scrofa
-
5.6.1.8 uterine smooth muscle
-
 Sus scrofa
-
5.6.1.8 uterus
-
 Sus scrofa
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
5.6.1.8 ATP + H2O + myosin bound to actin filament at position n
-
 Sus scrofa ADP + phosphate + myosin bound to actin filament at position n+1
-
 ?

Synonyms

EC Number Synonyms Comment Organism
5.6.1.8 myosin S1 ATPase
-
 Sus scrofa