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Literature summary extracted from
- Ca2+ removal by the plasma membrane Ca2+-ATPase influences the contribution of mitochondria to activity-dependent Ca2+ dynamics in Aplysia neuroendocrine cells (2016), J. Neurophysiol., 115, 2615-2634 .
Inhibitors
| EC Number | Inhibitors | Comment | Organism | Structure |
|---|---|---|---|---|
| 7.2.2.10 | Ca2+ | - |
Aplysia californica |  |
| 7.2.2.10 | carboxyeosin | - |
Aplysia californica | |
| 7.2.2.10 | DMSO | - |
Aplysia californica | |
| 7.2.2.10 | EGTA | - |
Aplysia californica | |
Localization
| EC Number | Localization | Comment | Organism | GeneOntology No. | Textmining |
|---|---|---|---|---|---|
| 7.2.2.10 | plasma membrane | - |
Aplysia californica | 5886 | - |
Metals/Ions
| EC Number | Metals/Ions | Comment | Organism | Structure |
|---|---|---|---|---|
| 7.2.2.10 | Ca2+ | required | Aplysia californica | |
Natural Substrates/ Products (Substrates)
| EC Number | Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
|---|---|---|---|---|---|---|---|
| 7.2.2.10 | ATP + H2O + Ca2+[side 1] | Aplysia californica | - |
ADP + phosphate + Ca2+[side 2] | - |
? | |
Organism
| EC Number | Organism | UniProt | Comment | Textmining |
|---|---|---|---|---|
| 7.2.2.10 | Aplysia californica | - |
- |
- |
Source Tissue
| EC Number | Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|---|
| 7.2.2.10 | bag cell neuron | - |
Aplysia californica | - |
| 7.2.2.10 | neuroendocrine cell | - |
Aplysia californica | - |
Substrates and Products (Substrate)
| EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|---|
| 7.2.2.10 | ATP + H2O + Ca2+[side 1] | - |
Aplysia californica | ADP + phosphate + Ca2+[side 2] | - |
? | |
Synonyms
| EC Number | Synonyms | Comment | Organism |
|---|---|---|---|
| 7.2.2.10 | plasma membrane Ca2+-ATPase | - |
Aplysia californica |
| 7.2.2.10 | PMCA | - |
Aplysia californica |
Ki Value [mM]
| EC Number | Ki Value [mM] | Ki Value maximum [mM] | Inhibitor | Comment | Organism | Structure |
|---|---|---|---|---|---|---|
| 7.2.2.10 | 0.00005 | - |
Ca2+ | pH and temperature not specified in the publication | Aplysia californica | |
General Information
| EC Number | General Information | Comment | Organism |
|---|---|---|---|
| 7.2.2.10 | metabolism | Ca2+ removal by the enzyme influences the propensity for stimulus-evoked Ca2+-induced Ca2+ release by adjusting the amount of Ca2+ available for mitochondrial Ca2+ uptake | Aplysia californica |
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