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Literature summary extracted from

  • Dougherty, M.; Downs, D.M.
    The stm4066 gene product of Salmonella enterica serovar Typhimurium has aminoimidazole riboside (AIRs) kinase activity and allows AIRs to satisfy the thiamine requirement of pur mutant strains (2003), J. Bacteriol., 185, 332-339 .
    View publication on PubMedView publication on EuropePMC

Cloned(Commentary)

EC Number Cloned (Comment) Organism
2.7.1.223 expression in Escherichia coli Salmonella enterica subsp. enterica serovar Typhimurium

Organism

EC Number Organism UniProt Comment Textmining
2.7.1.223 Salmonella enterica subsp. enterica serovar Typhimurium Q8ZKR2
-
-
2.7.1.223 Salmonella enterica subsp. enterica serovar Typhimurium ATCC 700720 Q8ZKR2
-
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2.7.1.223 ATP + 5-amino-1-(beta-D-ribosyl)imidazole
-
 Salmonella enterica subsp. enterica serovar Typhimurium ADP + 5-amino-1-(5-phospho-beta-D-ribosyl)imidazole
-
 ?
2.7.1.223 ATP + 5-amino-1-(beta-D-ribosyl)imidazole
-
 Salmonella enterica subsp. enterica serovar Typhimurium ATCC 700720 ADP + 5-amino-1-(5-phospho-beta-D-ribosyl)imidazole
-
 ?

Synonyms

EC Number Synonyms Comment Organism
2.7.1.223 STM4066
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 Salmonella enterica subsp. enterica serovar Typhimurium

General Information

EC Number General Information Comment Organism
2.7.1.223 physiological function lack of the Stm4066 gene product derepresses transcription of an associated operon (stm4065-4067) that encodes a predicted kinase. STM4066 in multicopy confers the ability to use aminoimidazole riboside as a source of thiamine. The Stm4066 gene product has aminoimidazole riboside kinase activity in vitro Salmonella enterica subsp. enterica serovar Typhimurium