EC Number | Crystallization (Comment) | Organism |
---|---|---|
3.2.2.23 | dynamic simulation of the pre-catalytic complex of Fpg with DNA containing oxoG opposite C or A, the latter in either syn or anti conformation. Only one transition is observed in the experimental reaction rate pH dependence plots, and Glu2 keeps the same set of interactions regardless of its protonation state. The adenine base opposite oxoG is highly distorting for the adjacent nucleotides. The side chains of Arg109 and Phe111 that Fpg inserts into DNA to maintain its kinked conformation tend to withdraw from their positions if A is opposite to the lesion | Lactococcus lactis |
EC Number | Organism | UniProt | Comment | Textmining |
---|---|---|---|---|
3.2.2.23 | Lactococcus lactis | P42371 | - |
- |
EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|---|
3.2.2.23 | DNA containing oxoG opposite C or A + H2O | - |
Lactococcus lactis | 2,6-diamino-4-hydroxy-5-formamidopyrimidine + DNA | - |
? |
EC Number | Synonyms | Comment | Organism |
---|---|---|---|
3.2.2.23 | FPG | - |
Lactococcus lactis |
3.2.2.23 | MutM | - |
Lactococcus lactis |