Any feedback?
Please rate this page
(literature.php)
(0/150)

BRENDA support

Literature summary extracted from

  • Maicas, S.; Guirao-Abad, J.; Argüelles, J.
    Yeast trehalases Two enzymes, one catalytic mission (2016), Biochim. Biophys. Acta, 1860, 2249-2254 .
    View publication on PubMed

Inhibitors

EC Number Inhibitors Comment Organism Structure
3.2.1.28 glucose the enzyme is regulated by glucose-induced catabolite repression Candida albicans
3.2.1.28 Mg2+
-
 Saccharomyces cerevisiae

Localization

EC Number Localization Comment Organism GeneOntology No. Textmining
3.2.1.28 cytosol
-
 Saccharomyces cerevisiae 5829
-
3.2.1.28 vacuole
-
 Candida albicans 5773
-

Metals/Ions

EC Number Metals/Ions Comment Organism Structure
3.2.1.28 Ca2+ activates Saccharomyces cerevisiae
3.2.1.28 Mn2+ activates Saccharomyces cerevisiae
3.2.1.28 additional information the activity is independent of divalent cations Candida albicans

Molecular Weight [Da]

EC Number Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
3.2.1.28 104000
-
 calculated from sequence Candida albicans

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
3.2.1.28 alpha,alpha-trehalose + H2O Candida albicans hydrolysis of exogenous trehalose beta-D-glucose + alpha-D-glucose
-
 ?
3.2.1.28 alpha,alpha-trehalose + H2O Saccharomyces cerevisiae hydrolysis of intracellular trehalose in response to physiological stimuli beta-D-glucose + alpha-D-glucose
-
 ?
3.2.1.28 alpha,alpha-trehalose + H2O Candida albicans ATCC MYA-2876 hydrolysis of exogenous trehalose beta-D-glucose + alpha-D-glucose
-
 ?
3.2.1.28 alpha,alpha-trehalose + H2O Saccharomyces cerevisiae ATCC 204508 hydrolysis of intracellular trehalose in response to physiological stimuli beta-D-glucose + alpha-D-glucose
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
3.2.1.28 Candida albicans Q5AAU5
-
-
3.2.1.28 Candida albicans ATCC MYA-2876 Q5AAU5
-
-
3.2.1.28 Saccharomyces cerevisiae P32356
-
-
3.2.1.28 Saccharomyces cerevisiae ATCC 204508 P32356
-
-

Posttranslational Modification

EC Number Posttranslational Modification Comment Organism
3.2.1.28 phosphoprotein the enzyme is regulated by reversible phosphorylation mediated by the cAMP-PKA pathway Saccharomyces cerevisiae

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
3.2.1.28 alpha,alpha-trehalose + H2O
-
 Saccharomyces cerevisiae beta-D-glucose + alpha-D-glucose
-
 ?
3.2.1.28 alpha,alpha-trehalose + H2O
-
 Candida albicans beta-D-glucose + alpha-D-glucose
-
 ?
3.2.1.28 alpha,alpha-trehalose + H2O hydrolysis of exogenous trehalose Candida albicans beta-D-glucose + alpha-D-glucose
-
 ?
3.2.1.28 alpha,alpha-trehalose + H2O hydrolysis of intracellular trehalose in response to physiological stimuli Saccharomyces cerevisiae beta-D-glucose + alpha-D-glucose
-
 ?
3.2.1.28 alpha,alpha-trehalose + H2O
-
 Candida albicans ATCC MYA-2876 beta-D-glucose + alpha-D-glucose
-
 ?
3.2.1.28 alpha,alpha-trehalose + H2O hydrolysis of exogenous trehalose Candida albicans ATCC MYA-2876 beta-D-glucose + alpha-D-glucose
-
 ?
3.2.1.28 alpha,alpha-trehalose + H2O
-
 Saccharomyces cerevisiae ATCC 204508 beta-D-glucose + alpha-D-glucose
-
 ?
3.2.1.28 alpha,alpha-trehalose + H2O hydrolysis of intracellular trehalose in response to physiological stimuli Saccharomyces cerevisiae ATCC 204508 beta-D-glucose + alpha-D-glucose
-
 ?

Synonyms

EC Number Synonyms Comment Organism
3.2.1.28 acid trehalase
-
 Candida albicans
3.2.1.28 ATC1
-
 Candida albicans
3.2.1.28 neutral trehalase
-
 Saccharomyces cerevisiae
3.2.1.28 NTH1
-
 Saccharomyces cerevisiae

Temperature Optimum [°C]

EC Number Temperature Optimum [°C] Temperature Optimum Maximum [°C] Comment Organism
3.2.1.28 30
-
-
 Saccharomyces cerevisiae
3.2.1.28 40
-
-
 Candida albicans

pH Optimum

EC Number pH Optimum Minimum pH Optimum Maximum Comment Organism
3.2.1.28 4.5 5
-
 Candida albicans
3.2.1.28 6.8 7
-
 Saccharomyces cerevisiae