Any feedback?
Please rate this page
(literature.php)
(0/150)

BRENDA support

Literature summary extracted from

  • Liu, W.Y.
    Research on ribosome-inactivating proteins from angiospermae to gymnospermae and cryptogamia (2017), Am. J. Transl. Res., 9, 5719-5742 .
    View publication on PubMedView publication on EuropePMC

Organism

EC Number Organism UniProt Comment Textmining
3.2.2.22 Cinnamomum camphora Q94BW3
-
-
3.2.2.22 Platycladus orientalis
-
 i.e. Biota orientalis
-
3.2.2.22 Saccharina japonica
-
-
-
3.2.2.22 Trichosanthes kirilowii
-
-
-

Posttranslational Modification

EC Number Posttranslational Modification Comment Organism
3.2.2.22 glycoprotein
-
 Cinnamomum camphora

Source Tissue

EC Number Source Tissue Comment Organism Textmining
3.2.2.22 seed
-
 Platycladus orientalis
-
3.2.2.22 seed
-
 Saccharina japonica
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
3.2.2.22 rat 28S rRNA + H2O
-
 Platycladus orientalis ?
-
 ?
3.2.2.22 rat 28S rRNA + H2O
-
 Saccharina japonica ?
-
 ?
3.2.2.22 rat 28S rRNA + H2O
-
 Trichosanthes kirilowii ?
-
 ?
3.2.2.22 rat 28S rRNA + H2O
-
 Cinnamomum camphora ?
-
 ?

Subunits

EC Number Subunits Comment Organism
3.2.2.22 ? x * 27000, SDS-PAGE Trichosanthes kirilowii
3.2.2.22 ? x * 61000, SDS-PAGE Cinnamomum camphora
3.2.2.22 ? x * 36000, SDS-PAGE Saccharina japonica
3.2.2.22 ? x * 13000, SDS-PAGE Platycladus orientalis

Synonyms

EC Number Synonyms Comment Organism
3.2.2.22 cinnamomin
-
 Cinnamomum camphora
3.2.2.22 lamjapin
-
 Saccharina japonica
3.2.2.22 RNase Bo
-
 Platycladus orientalis
3.2.2.22 trichosanthin
-
 Trichosanthes kirilowii

Temperature Stability [°C]

EC Number Temperature Stability Minimum [°C] Temperature Stability Maximum [°C] Comment Organism
3.2.2.22 100
-
 10 min, stable Platycladus orientalis

pI Value

EC Number Organism Comment pI Value Maximum pI Value
3.2.2.22 Saccharina japonica isoelectric focusing
-
 8.4

General Information

EC Number General Information Comment Organism
3.2.2.22 physiological function cinnamomin potently inhibits the in vitro protein synthesis in the rabbit reticulocyte lysate system or a reconstituted protein synthesis system composed of rat ribosome with IC50 value of about 9.7 nM. The cleavage of supercoiled double-stranded DNA is an intrinsic property of cinnamomin A-chain, its N- and C-terminal regions are required for deadenylation of rRNA and also necessary for deadenylation of supercoiled double-stranded circular DNA Cinnamomum camphora
3.2.2.22 physiological function lamjapin inhibits protein synthesis in the cell-free system of rabbit reticulocyte with an IC50 value of about 0.03-4 nM Saccharina japonica
3.2.2.22 physiological function trichosanthin is highly toxic to trophoblasts and choriocarcinoma cells. Low-density lipoprotein receptor-related protein 1 is an essential receptor for trichosanthin in 2-choriocarcinoma cell lines Trichosanthes kirilowii