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Literature summary extracted from

  • Grabarczyk, D.; Berks, B.
    Intermediates in the Sox sulfur oxidation pathway are bound to a sulfane conjugate of the carrier protein SoxYZ (2017), PLoS ONE, 12, e0173395 .
    View publication on PubMedView publication on EuropePMC

Metals/Ions

EC Number Metals/Ions Comment Organism Structure
3.1.6.20 Mn2+ contains Mn2+ Thermus thermophilus

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
2.8.5.2 [SoxY protein]-L-cysteine + thiosulfate + 2 ferricytochrome c Paracoccus pantotrophus the enzyme is part of the Sox enzyme system, which participates in a bacterial thiosulfate oxidation pathway that produces sulfate [SoxY protein]-S-sulfosulfanyl-L-cysteine + 2 ferrocytochrome c + 2 H+
-
?
2.8.5.2 [SoxY protein]-S-sulfanyl-L-cysteine + thiosulfate + 2 ferricytochrome c Paracoccus pantotrophus the enzyme is part of the Sox enzyme system, which participates in a bacterial thiosulfate oxidation pathway that produces sulfate [SoxY protein]-S-(2-sulfodisulfanyl)-L-cysteine + 2 ferrocytochrome c + 2 H+
-
?
3.1.6.20 [SoxYZ protein]-S-(2-sulfodisulfanyl)-L-cysteine + H2O Thermus thermophilus
-
[SoxYZ protein]-S-disulfanyl-L-cysteine + sulfate
-
?
3.1.6.20 [SoxYZ protein]-S-sulfosulfanyl-L-cysteine + H2O Thermus thermophilus
-
[SoxYZ protein]-S-sulfanyl-L-cysteine + sulfate
-
?

Organism

EC Number Organism UniProt Comment Textmining
2.8.5.2 Paracoccus pantotrophus O33434 AND Q9LCV0 O33434: subunit SoxA, Q9LCV0: subunit SoxX
-
3.1.6.20 Thermus thermophilus
-
-
-

Purification (Commentary)

EC Number Purification (Comment) Organism
3.1.6.20 ammonium sulfate precipitation and Hitrap pheny lcolumn chromatography Thermus thermophilus

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2.8.5.2 [SoxY protein]-L-cysteine + thiosulfate + 2 ferricytochrome c the enzyme is part of the Sox enzyme system, which participates in a bacterial thiosulfate oxidation pathway that produces sulfate Paracoccus pantotrophus [SoxY protein]-S-sulfosulfanyl-L-cysteine + 2 ferrocytochrome c + 2 H+
-
?
2.8.5.2 [SoxY protein]-L-cysteine + thiosulfate + 2 ferricytochrome c the enzyme catalyses two reactions in the pathway - early in the pathway it attaches a thiosulfate molecule to the sulfur atom of an L-cysteine of a SoxY protein; later it transfers a second thiosulfate molecule to a sulfane group that is already attached to the same cysteine residue Paracoccus pantotrophus [SoxY protein]-S-sulfosulfanyl-L-cysteine + 2 ferrocytochrome c + 2 H+
-
?
2.8.5.2 [SoxY protein]-S-sulfanyl-L-cysteine + thiosulfate + 2 ferricytochrome c the enzyme is part of the Sox enzyme system, which participates in a bacterial thiosulfate oxidation pathway that produces sulfate Paracoccus pantotrophus [SoxY protein]-S-(2-sulfodisulfanyl)-L-cysteine + 2 ferrocytochrome c + 2 H+
-
?
2.8.5.2 [SoxY protein]-S-sulfanyl-L-cysteine + thiosulfate + 2 ferricytochrome c the enzyme catalyses two reactions in the pathway - early in the pathway it attaches a thiosulfate molecule to the sulfur atom of a L-cysteine of a SoxY protein; later it transfers a second thiosulfate molecule to a sulfane group that is already attached to the same cysteine residue Paracoccus pantotrophus [SoxY protein]-S-(2-sulfodisulfanyl)-L-cysteine + 2 ferrocytochrome c + 2 H+
-
?
3.1.6.20 [SoxYZ protein]-S-(2-sulfodisulfanyl)-L-cysteine + H2O
-
Thermus thermophilus [SoxYZ protein]-S-disulfanyl-L-cysteine + sulfate
-
?
3.1.6.20 [SoxYZ protein]-S-sulfosulfanyl-L-cysteine + H2O
-
Thermus thermophilus [SoxYZ protein]-S-sulfanyl-L-cysteine + sulfate
-
?

Synonyms

EC Number Synonyms Comment Organism
2.8.5.2 SoxAX
-
Paracoccus pantotrophus
3.1.6.20 SoxB
-
Thermus thermophilus

General Information

EC Number General Information Comment Organism
2.8.5.2 metabolism the enzyme is part of the Sox enzyme system, which participates in a bacterial thiosulfate oxidation pathway that produces sulfate Paracoccus pantotrophus