BRENDA - Enzyme Database show

Characterization of recombinant dihydrodipicolinate synthase from the bread wheat Triticum aestivum

Gupta, R.; Hogan, C.J.; Perugini, M.A.; Soares da Costa, T.P.; Planta 248, 381-391 (2018)

Data extracted from this reference:

Cloned(Commentary)
EC Number
Commentary
Organism
4.3.3.7
expression in Escherichia coli
Triticum aestivum
Inhibitors
EC Number
Inhibitors
Commentary
Organism
Structure
4.3.3.7
L-lysine
-
Triticum aestivum
KM Value [mM]
EC Number
KM Value [mM]
KM Value Maximum [mM]
Substrate
Commentary
Organism
Structure
4.3.3.7
0.07
-
L-aspartate-4-semialdehyde
pH 8.0, 30°C
Triticum aestivum
4.3.3.7
0.45
-
pyruvate
pH 8.0, 30°C
Triticum aestivum
Natural Substrates/ Products (Substrates)
EC Number
Natural Substrates
Organism
Commentary (Nat. Sub.)
Natural Products
Commentary (Nat. Pro.)
Organism (Nat. Pro.)
Reversibility
4.3.3.7
pyruvate + L-aspartate-4-semialdehyde
Triticum aestivum
the enzyme catalyzes the first committed step in the lysine biosynthesis pathway of plants
(2S,4S)-4-hydroxy-2,3,4,5-tetrahydrodipicolinate + H2O
-
-
?
Organism
EC Number
Organism
Primary Accession No. (UniProt)
Commentary
Textmining
4.3.3.7
Triticum aestivum
P24846
-
-
Purification (Commentary)
EC Number
Commentary
Organism
4.3.3.7
-
Triticum aestivum
Substrates and Products (Substrate)
EC Number
Substrates
Commentary Substrates
Literature (Substrates)
Organism
Products
Commentary (Products)
Literature (Products)
Organism (Products)
Reversibility
4.3.3.7
pyruvate + L-aspartate-4-semialdehyde
the enzyme catalyzes the first committed step in the lysine biosynthesis pathway of plants
749039
Triticum aestivum
(2S,4S)-4-hydroxy-2,3,4,5-tetrahydrodipicolinate + H2O
-
-
-
?
Subunits
EC Number
Subunits
Commentary
Organism
4.3.3.7
tetramer
-
Triticum aestivum
Turnover Number [1/s]
EC Number
Turnover Number Minimum [1/s]
Turnover Number Maximum [1/s]
Substrate
Commentary
Organism
Structure
4.3.3.7
56
-
L-aspartate-4-semialdehyde
pH 8.0, 30°C
Triticum aestivum
IC50 Value
EC Number
IC50 Value
IC50 Value Maximum
Commentary
Organism
Inhibitor
Structure
4.3.3.7
0.033
-
pH 8.0, 30°C
Triticum aestivum
L-lysine
Cloned(Commentary) (protein specific)
EC Number
Commentary
Organism
4.3.3.7
expression in Escherichia coli
Triticum aestivum
IC50 Value (protein specific)
EC Number
IC50 Value
IC50 Value Maximum
Commentary
Organism
Inhibitor
Structure
4.3.3.7
0.033
-
pH 8.0, 30°C
Triticum aestivum
L-lysine
Inhibitors (protein specific)
EC Number
Inhibitors
Commentary
Organism
Structure
4.3.3.7
L-lysine
-
Triticum aestivum
KM Value [mM] (protein specific)
EC Number
KM Value [mM]
KM Value Maximum [mM]
Substrate
Commentary
Organism
Structure
4.3.3.7
0.07
-
L-aspartate-4-semialdehyde
pH 8.0, 30°C
Triticum aestivum
4.3.3.7
0.45
-
pyruvate
pH 8.0, 30°C
Triticum aestivum
Natural Substrates/ Products (Substrates) (protein specific)
EC Number
Natural Substrates
Organism
Commentary (Nat. Sub.)
Natural Products
Commentary (Nat. Pro.)
Organism (Nat. Pro.)
Reversibility
4.3.3.7
pyruvate + L-aspartate-4-semialdehyde
Triticum aestivum
the enzyme catalyzes the first committed step in the lysine biosynthesis pathway of plants
(2S,4S)-4-hydroxy-2,3,4,5-tetrahydrodipicolinate + H2O
-
-
?
Purification (Commentary) (protein specific)
EC Number
Commentary
Organism
4.3.3.7
-
Triticum aestivum
Substrates and Products (Substrate) (protein specific)
EC Number
Substrates
Commentary Substrates
Literature (Substrates)
Organism
Products
Commentary (Products)
Literature (Products)
Organism (Products)
Reversibility
4.3.3.7
pyruvate + L-aspartate-4-semialdehyde
the enzyme catalyzes the first committed step in the lysine biosynthesis pathway of plants
749039
Triticum aestivum
(2S,4S)-4-hydroxy-2,3,4,5-tetrahydrodipicolinate + H2O
-
-
-
?
Subunits (protein specific)
EC Number
Subunits
Commentary
Organism
4.3.3.7
tetramer
-
Triticum aestivum
Turnover Number [1/s] (protein specific)
EC Number
Turnover Number Minimum [1/s]
Turnover Number Maximum [1/s]
Substrate
Commentary
Organism
Structure
4.3.3.7
56
-
L-aspartate-4-semialdehyde
pH 8.0, 30°C
Triticum aestivum
General Information
EC Number
General Information
Commentary
Organism
4.3.3.7
metabolism
the enzyme catalyzes the first committed step in the lysine biosynthesis pathway of plants
Triticum aestivum
General Information (protein specific)
EC Number
General Information
Commentary
Organism
4.3.3.7
metabolism
the enzyme catalyzes the first committed step in the lysine biosynthesis pathway of plants
Triticum aestivum