Any feedback?
Please rate this page
(literature.php)
(0/150)

BRENDA support

Literature summary extracted from

  • Wang, X.; Gao, J.; Zhu, Z.; Dong, X.; Wang, X.; Ren, G.; Zhou, X.; Kuai, B.
    TCP transcription factors are critical for the coordinated regulation of isochorismate synthase 1 expression in Arabidopsis thaliana (2015), Plant J., 82, 151-162 .
    View publication on PubMed

Cloned(Commentary)

EC Number Cloned (Comment) Organism
5.4.4.2 gene ICS1, yeast one-hybrid (Y1H) screening and transactivation activity assay in Saccharomyces cerevisiae strain YM4271 Arabidopsis thaliana

Localization

EC Number Localization Comment Organism GeneOntology No. Textmining
5.4.4.2 chloroplast
-
 Arabidopsis thaliana 9507
-

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
5.4.4.2 Chorismate Arabidopsis thaliana
-
 Isochorismate
-
 r
5.4.4.2 Chorismate Arabidopsis thaliana Col-0
-
 Isochorismate
-
 r

Organism

EC Number Organism UniProt Comment Textmining
5.4.4.2 Arabidopsis thaliana Q9S7H8
-
-
5.4.4.2 Arabidopsis thaliana Col-0 Q9S7H8
-
-

Purification (Commentary)

EC Number Purification (Comment) Organism
5.4.4.2 isolation of protoplasts Arabidopsis thaliana

Source Tissue

EC Number Source Tissue Comment Organism Textmining
5.4.4.2 leaf
-
 Arabidopsis thaliana
-
5.4.4.2 seedling
-
 Arabidopsis thaliana
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
5.4.4.2 Chorismate
-
 Arabidopsis thaliana Isochorismate
-
 r
5.4.4.2 Chorismate
-
 Arabidopsis thaliana Col-0 Isochorismate
-
 r

Synonyms

EC Number Synonyms Comment Organism
5.4.4.2 ICS1
-
 Arabidopsis thaliana
5.4.4.2 isochorismate synthase 1
-
 Arabidopsis thaliana

Expression

EC Number Organism Comment Expression
5.4.4.2 Arabidopsis thaliana a significant reduction in the expression of ICS1 during immune responses is observed in the tcp8 tcp9 double mutant. There is a strong negative regulatory region between -128 and -316 bp, and the binding of repressor(s) to this region may be necessary for suppression of ICS1 expression during plant growth and development, TCP8 can bind at this region, while TCP5, TCP11 and TCP19 appear not to bind to the promoter region. TCP8 specifically binds to the TCP binding site in the ICS1 promoter in vitro and in vivo down
5.4.4.2 Arabidopsis thaliana isozyme ICS1 expression is positively regulated by TCP family transcription factor AtTCP8, e.g. under pathogen attack of Pseudomonas syringae pv. maculicola ES4326. TCP8/TCP9 positively regulate ICS1 expression with redundancy upon pathogen infection, and TCPs are involved in maintaining ICS1 expression up

General Information

EC Number General Information Comment Organism
5.4.4.2 malfunction significant reduction in the expression of ICS1 during immune responses is observed in the tcp8/tcp9 double mutant Arabidopsis thaliana
5.4.4.2 metabolism isochorismate synthase 1 is a key enzyme in salicylate biosynthesis in Arabidopsis thaliana. The TCP family transcription factor AtTCP8 is a regulator of isozyme ICS1, it binds to a typical TCP binding site in the ICS1 promoter. Expression patterns of TCP8 and its corresponding gene TCP9 largely overlap with ICS1 under pathogen attack. Strong interactions between TCP8 and SAR deficient 1 (SARD1), WRKY family transcription factor 28 (WRKY28), NAC (NAM/ATAF1, ATAF2/CUC2) family transcription factor 019 (NAC019), as well as among TCP8, TCP9 and TCP20, implying a complex coordinated regulatory mechanism underlying ICS1 expression. There is a strong negative regulatory region between -128 and -316 bp, and the binding of repressor(s) to this region may be necessary for suppression of ICS1 expression during plant growth and development, TCP8 can bind at this region, while TCP5, TCP11 and TCP19 appear not to bind to the promoter region. TCP8 specifically binds to the TCP binding site in the ICS1 promoter in vitro and in vivo. Trans-activation capability of TCP8. TCP8/TCP9 positively regulate ICS1 expression with redundancy upon pathogen infection, and TCPs are involved in maintaining ICS1 expression, yeast one-hybrid (Y1H) screening and transactivation activity assay, detailed overview Arabidopsis thaliana