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Literature summary extracted from

  • Kaczmarzyk, D.; Cengic, I.; Yao, L.; Hudson, E.P.
    Diversion of the long-chain acyl-ACP pool in Synechocystis to fatty alcohols through CRISPRi repression of the essential phosphate acyltransferase PlsX (2018), Metab. Eng., 45, 59-66 .
    View publication on PubMed

Cloned(Commentary)

EC Number Cloned (Comment) Organism
1.2.1.80 expressed in Synechocystis sp. PCC 6803 Oryza sativa

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
1.2.1.80 oleoyl-[acyl carrier protein] + NADPH + H+ Synechocystis sp. PCC 6803
-
 oleic aldehyde + acyl carrier protein + NADP+
-
 ?
1.2.1.80 palmitoyl-[acyl carrier protein] + NADPH + H+ Synechocystis sp. PCC 6803
-
 hexadecanal + acyl carrier protein + NADP+
-
 ?
1.2.1.80 palmitoyl-[acyl carrier protein] + NADPH + H+ Oryza sativa specific substrate hexadecanal + acyl carrier protein + NADP+
-
 ?
1.2.1.80 stearoyl-[acyl carrier protein] + NADPH + H+ Synechocystis sp. PCC 6803
-
 stearoylaldehyde + acyl carrier protein + NADP+
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
1.2.1.80 Oryza sativa
-
-
-
1.2.1.80 Synechocystis sp. PCC 6803
-
-
-
2.3.1.274 Synechocystis sp. PCC 6803 P73950
-
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
1.2.1.80 oleoyl-[acyl carrier protein] + NADPH + H+
-
 Synechocystis sp. PCC 6803 oleic aldehyde + acyl carrier protein + NADP+
-
 ?
1.2.1.80 palmitoyl-[acyl carrier protein] + NADPH + H+
-
 Synechocystis sp. PCC 6803 hexadecanal + acyl carrier protein + NADP+
-
 ?
1.2.1.80 palmitoyl-[acyl carrier protein] + NADPH + H+ specific substrate Oryza sativa hexadecanal + acyl carrier protein + NADP+
-
 ?
1.2.1.80 stearoyl-[acyl carrier protein] + NADPH + H+
-
 Synechocystis sp. PCC 6803 stearoylaldehyde + acyl carrier protein + NADP+
-
 ?
2.3.1.274 hexadecanoyl-[acyl-carrier protein] + phosphate the enzyme is involved in phosphatidic acid synthesis Synechocystis sp. PCC 6803 hexadecanoyl phosphate + an [acyl-carrier protein]
-
 ?
2.3.1.274 octadecanoyl-[acyl-carrier protein] + phosphate
-
 Synechocystis sp. PCC 6803 octadecanoyl phosphate + an [acyl-carrier protein]
-
 ?

Synonyms

EC Number Synonyms Comment Organism
1.2.1.80 AAR
-
 Synechocystis sp. PCC 6803
1.2.1.80 acyl-ACP reductase
-
 Oryza sativa
1.2.1.80 acyl-ACP reductase
-
 Synechocystis sp. PCC 6803
1.2.1.80 DPW gene name, defective pollen wall Oryza sativa
1.2.1.80 fatty acyl-ACP reductase
-
 Oryza sativa
1.2.1.80 fatty acyl-ACP reductase
-
 Synechocystis sp. PCC 6803
1.2.1.80 sll0209
-
 Synechocystis sp. PCC 6803
2.3.1.274 phosphate acyltransferase PlsX
-
 Synechocystis sp. PCC 6803
2.3.1.274 slr1510
-
 Synechocystis sp. PCC 6803

Cofactor

EC Number Cofactor Comment Organism Structure
1.2.1.80 NADPH
-
 Oryza sativa
1.2.1.80 NADPH
-
 Synechocystis sp. PCC 6803

General Information

EC Number General Information Comment Organism
2.3.1.274 malfunction repression of slr1510 increases octadecanol productivity threefold over the base strain. Accumulation of fatty alcohols impairs growth, alters the membrane composition, and causes a build-up of reactive oxygen species Synechocystis sp. PCC 6803
2.3.1.274 metabolism the enzyme is involved in phosphatidic acid synthesis Synechocystis sp. PCC 6803