BRENDA - Enzyme Database show

Development of pH-independent drug release formulation using lipocalin-type prostaglandin D synthase

Mizoguchi, M.; Nakatsuji, M.; Takano, J.; Ishibashi, O.; Wada, K.; Inui, T.; J. Pharm. Sci. 105, 2735-2742 (2016)

Data extracted from this reference:

Engineering
EC Number
Amino acid exchange
Commentary
Organism
5.3.99.2
C65A/C167A
the mutations abolish enzymatic activity
Homo sapiens
Natural Substrates/ Products (Substrates)
EC Number
Natural Substrates
Organism
Commentary (Nat. Sub.)
Natural Products
Commentary (Nat. Pro.)
Organism (Nat. Pro.)
Reversibility
5.3.99.2
Prostaglandin H2
Homo sapiens
-
Prostaglandin D2
-
-
?
Organism
EC Number
Organism
Primary Accession No. (UniProt)
Commentary
Textmining
5.3.99.2
Homo sapiens
P41222
-
-
Substrates and Products (Substrate)
EC Number
Substrates
Commentary Substrates
Literature (Substrates)
Organism
Products
Commentary (Products)
Literature (Products)
Organism (Products)
Reversibility
5.3.99.2
Prostaglandin H2
-
748455
Homo sapiens
Prostaglandin D2
-
-
-
?
Engineering (protein specific)
EC Number
Amino acid exchange
Commentary
Organism
5.3.99.2
C65A/C167A
the mutations abolish enzymatic activity
Homo sapiens
Natural Substrates/ Products (Substrates) (protein specific)
EC Number
Natural Substrates
Organism
Commentary (Nat. Sub.)
Natural Products
Commentary (Nat. Pro.)
Organism (Nat. Pro.)
Reversibility
5.3.99.2
Prostaglandin H2
Homo sapiens
-
Prostaglandin D2
-
-
?
Substrates and Products (Substrate) (protein specific)
EC Number
Substrates
Commentary Substrates
Literature (Substrates)
Organism
Products
Commentary (Products)
Literature (Products)
Organism (Products)
Reversibility
5.3.99.2
Prostaglandin H2
-
748455
Homo sapiens
Prostaglandin D2
-
-
-
?