BRENDA - Enzyme Database show

Human thromboxane synthase Comparative modeling and docking evaluation with the competitive inhibitors dazoxiben and ozagrel

Sathler, P.; Santana, M.; Lourenço, A.; Rodrigues, C.; Abreu, P.; Cabral, L.; Castro, H.; J. Enzyme Inhib. Med. Chem. 29, 527-531 (2014)

Data extracted from this reference:

Inhibitors
EC Number
Inhibitors
Commentary
Organism
Structure
5.3.99.5
dazoxiben
competitive inhibitor
Homo sapiens
5.3.99.5
ozagrel
competitive inhibitor
Homo sapiens
Natural Substrates/ Products (Substrates)
EC Number
Natural Substrates
Organism
Commentary (Nat. Sub.)
Natural Products
Commentary (Nat. Pro.)
Organism (Nat. Pro.)
Reversibility
5.3.99.5
prostaglandin H2
Homo sapiens
-
thromboxane A2 + ?
-
-
?
Organism
EC Number
Organism
Primary Accession No. (UniProt)
Commentary
Textmining
5.3.99.5
Homo sapiens
-
-
-
Substrates and Products (Substrate)
EC Number
Substrates
Commentary Substrates
Literature (Substrates)
Organism
Products
Commentary (Products)
Literature (Products)
Organism (Products)
Reversibility
5.3.99.5
prostaglandin H2
-
748300
Homo sapiens
thromboxane A2 + ?
-
-
-
?
Inhibitors (protein specific)
EC Number
Inhibitors
Commentary
Organism
Structure
5.3.99.5
dazoxiben
competitive inhibitor
Homo sapiens
5.3.99.5
ozagrel
competitive inhibitor
Homo sapiens
Natural Substrates/ Products (Substrates) (protein specific)
EC Number
Natural Substrates
Organism
Commentary (Nat. Sub.)
Natural Products
Commentary (Nat. Pro.)
Organism (Nat. Pro.)
Reversibility
5.3.99.5
prostaglandin H2
Homo sapiens
-
thromboxane A2 + ?
-
-
?
Substrates and Products (Substrate) (protein specific)
EC Number
Substrates
Commentary Substrates
Literature (Substrates)
Organism
Products
Commentary (Products)
Literature (Products)
Organism (Products)
Reversibility
5.3.99.5
prostaglandin H2
-
748300
Homo sapiens
thromboxane A2 + ?
-
-
-
?