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Literature summary extracted from
- A novel A3 group aconitase tolerates oxidation and nitric oxide (2015), J. Biol. Chem., 290, 1412-1421 .
Inhibitors
| EC Number | Inhibitors | Comment | Organism | Structure |
|---|---|---|---|---|
| 4.2.1.3 | nitrite | inactivation rate constant is 0.0078/min, which is 1.6- and 7.8fold lower than those for AcnA4 and AcnB, respectively. When exposed to NO2-, the acnA3 mutant accumulates higher levels of cellular citrate compared with the other aconitase mutants | Achromobacter denitrificans |  |
| 4.2.1.3 | oxygen | atmospheric oxygen inactivates isoform AcnA3 at a rate of 0.0016/min, which is 2.7- and 37fold lower compared with isoforms AcnA4 and AcnB, respectively | Achromobacter denitrificans | |
Organism
| EC Number | Organism | UniProt | Comment | Textmining |
|---|---|---|---|---|
| 4.2.1.3 | Achromobacter denitrificans | A0A090AMG4 | - |
- |
| 4.2.1.3 | Achromobacter denitrificans YD35 | A0A090AMG4 | - |
- |
Synonyms
| EC Number | Synonyms | Comment | Organism |
|---|---|---|---|
| 4.2.1.3 | AcnA3 | - |
Achromobacter denitrificans |
Cofactor
| EC Number | Cofactor | Comment | Organism | Structure |
|---|---|---|---|---|
| 4.2.1.3 | [4Fe-4S]-center | the [4Fe-4S]2+ cluster of AcnA3 is more stable against oxidative inactivation by ferricyanide than that of isoform AcnA4 | Achromobacter denitrificans | |
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Release 2023.1 (January 2023)
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