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Literature summary extracted from

  • Chen, P.; Van Vliet, F.; Van De Casteele, M.; Legrain, C.; Cunin, R.; Glansdorff, N.
    Aspartate transcarbamylase from the hyperthermophilic eubacterium Thermotoga maritima Fused catalytic and regulatory polypeptides form an allosteric enzyme (1998), J. Bacteriol., 180, 6389-6391 .
    View publication on PubMedView publication on EuropePMC

Activating Compound

EC Number Activating Compound Comment Organism Structure
2.1.3.2 ATP 2 mM, activates Thermotoga maritima

Cloned(Commentary)

EC Number Cloned (Comment) Organism
2.1.3.2 expression in Escherichia coli. The catalytic and regulatory functions which, in the class B ATCases from members of the Enterobacteriaceae, Vibrio sp., and archaea, are carried out by specialized polypeptides, are combined on a single type of polypeptide assembled in trimers Thermotoga maritima

Inhibitors

EC Number Inhibitors Comment Organism Structure
2.1.3.2 CTP 2 mM, about 90% inhibition Thermotoga maritima
2.1.3.2 UTP 2 mM, about 90% inhibition Thermotoga maritima

Molecular Weight [Da]

EC Number Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
2.1.3.2 200000
-
 gel filtration Thermotoga maritima

Organism

EC Number Organism UniProt Comment Textmining
2.1.3.2 Thermotoga maritima P96111
-
-
2.1.3.2 Thermotoga maritima DSM 3109 P96111
-
-

Purification (Commentary)

EC Number Purification (Comment) Organism
2.1.3.2
-
 Thermotoga maritima

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2.1.3.2 carbamoyl phosphate + L-aspartate
-
 Thermotoga maritima phosphate + N-carbamoyl-L-aspartate
-
 ?
2.1.3.2 carbamoyl phosphate + L-aspartate
-
 Thermotoga maritima DSM 3109 phosphate + N-carbamoyl-L-aspartate
-
 ?

Subunits

EC Number Subunits Comment Organism
2.1.3.2 trimer 3 * 60500, calculated from sequence Thermotoga maritima

Synonyms

EC Number Synonyms Comment Organism
2.1.3.2 aspartate transcarbamylase
-
 Thermotoga maritima
2.1.3.2 ATCase
-
 Thermotoga maritima