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Literature summary extracted from

  • Virtue, S.; Masoodi, M.; de Weijer, B.A.; van Eijk, M.; Mok, C.Y.; Eiden, M.; Dale, M.; Pirraco, A.; Serlie, M.J.; Griffin, J.L.; Vidal-Puig, A.
    Prostaglandin profiling reveals a role for haematopoietic prostaglandin D synthase in adipose tissue macrophage polarisation in mice and humans (2015), Int. J. Obes., 39, 1151-1160 .
    View publication on PubMedView publication on EuropePMC

Inhibitors

EC Number Inhibitors Comment Organism Structure
5.3.99.2 HQL-79
-
 Homo sapiens
5.3.99.2 HQL-79
-
 Mus musculus

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
5.3.99.2 Prostaglandin H2 Homo sapiens
-
 Prostaglandin D2
-
 ?
5.3.99.2 Prostaglandin H2 Mus musculus
-
 Prostaglandin D2
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
5.3.99.2 Homo sapiens O60760
-
-
5.3.99.2 Mus musculus Q9JHF7
-
-

Source Tissue

EC Number Source Tissue Comment Organism Textmining
5.3.99.2 macrophage
-
 Homo sapiens
-
5.3.99.2 macrophage
-
 Mus musculus
-
5.3.99.2 white adipose tissue
-
 Homo sapiens
-
5.3.99.2 white adipose tissue
-
 Mus musculus
-

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
5.3.99.2 Prostaglandin H2
-
 Homo sapiens Prostaglandin D2
-
 ?
5.3.99.2 Prostaglandin H2
-
 Mus musculus Prostaglandin D2
-
 ?

Synonyms

EC Number Synonyms Comment Organism
5.3.99.2 H-PGDS
-
 Homo sapiens
5.3.99.2 H-PGDS
-
 Mus musculus
5.3.99.2 haematopoietic prostaglandin D synthase
-
 Homo sapiens
5.3.99.2 haematopoietic prostaglandin D synthase
-
 Mus musculus