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Literature summary extracted from

  • Sun, Z.; Shen, B.; Wu, H.; Zhou, X.; Wang, Q.; Xiao, J.; Zhang, Y.
    The secreted fructose 1,6-bisphosphate aldolase as a broad spectrum vaccine candidate against pathogenic bacteria in aquaculture (2015), Fish Shellfish Immunol., 46, 638-647 .
    View publication on PubMed

Application

EC Number Application Comment Organism
4.1.2.13 agriculture the enzyme can be utilized as a broad-spectrum vaccine against various pathogenic bacteria of aquaculture in the future Edwardsiella tarda
4.1.2.13 agriculture the enzyme can be utilized as a broad-spectrum vaccine against various pathogenic bacteria of aquaculture in the future Vibrio anguillarum
4.1.2.13 agriculture the enzyme can be utilized as a broad-spectrum vaccine against various pathogenic bacteria of aquaculture in the future Aeromonas hydrophila
4.1.2.13 agriculture the enzyme can be utilized as a broad-spectrum vaccine against various pathogenic bacteria of aquaculture in the future Vibrio campbellii
4.1.2.13 agriculture the enzyme can be utilized as a broad-spectrum vaccine against various pathogenic bacteria of aquaculture in the future Vibrio alginolyticus
4.1.2.13 drug development the enzyme can be utilized as a broad-spectrum vaccine against various pathogenic bacteria of aquaculture in the future Edwardsiella tarda
4.1.2.13 drug development the enzyme can be utilized as a broad-spectrum vaccine against various pathogenic bacteria of aquaculture in the future Vibrio anguillarum
4.1.2.13 drug development the enzyme can be utilized as a broad-spectrum vaccine against various pathogenic bacteria of aquaculture in the future Aeromonas hydrophila
4.1.2.13 drug development the enzyme can be utilized as a broad-spectrum vaccine against various pathogenic bacteria of aquaculture in the future Vibrio campbellii
4.1.2.13 drug development the enzyme can be utilized as a broad-spectrum vaccine against various pathogenic bacteria of aquaculture in the future Vibrio alginolyticus
4.1.2.13 medicine the enzyme can be utilized as a broad-spectrum vaccine against various pathogenic bacteria of aquaculture Vibrio harveyi
4.1.2.13 medicine the enzyme can be utilized as a broad-spectrum vaccine against various pathogenic bacteria of aquaculture Aeromonas hydrophila
4.1.2.13 medicine the enzyme can be utilized as a broad-spectrum vaccine against various pathogenic bacteria of aquaculture Vibrio alginolyticus
4.1.2.13 medicine the enzyme can be utilized as a broad-spectrum vaccine against various pathogenic bacteria of aquaculture Vibrio anguillarum
4.1.2.13 medicine the enzyme can be utilized as a broad-spectrum vaccine against various pathogenic bacteria of aquaculture Edwardsiella tarda

Cloned(Commentary)

EC Number Cloned (Comment) Organism
4.1.2.13 expressed in Escherichia coli BL21(DE3) cells Vibrio harveyi
4.1.2.13 expressed in Escherichia coli BL21(DE3) cells Aeromonas hydrophila
4.1.2.13 expressed in Escherichia coli BL21(DE3) cells Vibrio alginolyticus
4.1.2.13 expressed in Escherichia coli BL21(DE3) cells Vibrio anguillarum
4.1.2.13 expressed in Escherichia coli BL21(DE3) cells Edwardsiella tarda
4.1.2.13 expression in Escherichia coli Edwardsiella tarda
4.1.2.13 expression in Escherichia coli Vibrio anguillarum
4.1.2.13 expression in Escherichia coli Aeromonas hydrophila
4.1.2.13 expression in Escherichia coli Vibrio campbellii
4.1.2.13 expression in Escherichia coli Vibrio alginolyticus

Localization

EC Number Localization Comment Organism GeneOntology No. Textmining
4.1.2.13 extracellular
-
 Edwardsiella tarda
-
-
4.1.2.13 extracellular
-
 Vibrio anguillarum
-
-
4.1.2.13 extracellular
-
 Aeromonas hydrophila
-
-
4.1.2.13 extracellular
-
 Vibrio campbellii
-
-
4.1.2.13 extracellular
-
 Vibrio alginolyticus
-
-
4.1.2.13 membrane
-
 Edwardsiella tarda 16020
-
4.1.2.13 membrane
-
 Vibrio anguillarum 16020
-
4.1.2.13 membrane
-
 Aeromonas hydrophila 16020
-
4.1.2.13 membrane
-
 Vibrio campbellii 16020
-
4.1.2.13 membrane
-
 Vibrio alginolyticus 16020
-
4.1.2.13 periplasm
-
 Edwardsiella tarda
-
-
4.1.2.13 periplasm
-
 Vibrio anguillarum
-
-
4.1.2.13 periplasm
-
 Aeromonas hydrophila
-
-
4.1.2.13 periplasm
-
 Vibrio campbellii
-
-
4.1.2.13 periplasm
-
 Vibrio alginolyticus
-
-

Natural Substrates/ Products (Substrates)

EC Number Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
4.1.2.13 D-fructose 1,6-bisphosphate Vibrio harveyi
-
 glycerone phosphate + D-glyceraldehyde 3-phosphate
-
 ?
4.1.2.13 D-fructose 1,6-bisphosphate Aeromonas hydrophila
-
 glycerone phosphate + D-glyceraldehyde 3-phosphate
-
 ?
4.1.2.13 D-fructose 1,6-bisphosphate Vibrio alginolyticus
-
 glycerone phosphate + D-glyceraldehyde 3-phosphate
-
 ?
4.1.2.13 D-fructose 1,6-bisphosphate Vibrio anguillarum
-
 glycerone phosphate + D-glyceraldehyde 3-phosphate
-
 ?
4.1.2.13 D-fructose 1,6-bisphosphate Edwardsiella tarda
-
 glycerone phosphate + D-glyceraldehyde 3-phosphate
-
 ?
4.1.2.13 D-fructose 1,6-bisphosphate Vibrio harveyi ATCC BAA-1116
-
 glycerone phosphate + D-glyceraldehyde 3-phosphate
-
 ?
4.1.2.13 D-fructose 1,6-bisphosphate Vibrio anguillarum MVM425
-
 glycerone phosphate + D-glyceraldehyde 3-phosphate
-
 ?
4.1.2.13 D-fructose 1,6-bisphosphate Edwardsiella tarda EIB202
-
 glycerone phosphate + D-glyceraldehyde 3-phosphate
-
 ?
4.1.2.13 D-fructose 1,6-bisphosphate Vibrio alginolyticus 12G01
-
 glycerone phosphate + D-glyceraldehyde 3-phosphate
-
 ?
4.1.2.13 D-fructose 1,6-bisphosphate Aeromonas hydrophila ATCC7699
-
 glycerone phosphate + D-glyceraldehyde 3-phosphate
-
 ?

Organism

EC Number Organism UniProt Comment Textmining
4.1.2.13 Aeromonas hydrophila
-
-
-
4.1.2.13 Aeromonas hydrophila A0KGD4
-
-
4.1.2.13 Aeromonas hydrophila ATCC 7699 A0KGD4
-
-
4.1.2.13 Aeromonas hydrophila ATCC7699
-
-
-
4.1.2.13 Edwardsiella tarda
-
-
-
4.1.2.13 Edwardsiella tarda D0ZEE4
-
-
4.1.2.13 Edwardsiella tarda EIB202
-
-
-
4.1.2.13 Edwardsiella tarda EIB202 D0ZEE4
-
-
4.1.2.13 Vibrio alginolyticus
-
-
-
4.1.2.13 Vibrio alginolyticus A7MTQ6
-
-
4.1.2.13 Vibrio alginolyticus 12G01
-
-
-
4.1.2.13 Vibrio alginolyticus 12G01 A7MTQ6
-
-
4.1.2.13 Vibrio anguillarum
-
-
-
4.1.2.13 Vibrio anguillarum D0ZEE4
-
-
4.1.2.13 Vibrio anguillarum MVM425
-
-
-
4.1.2.13 Vibrio anguillarum MVM425 D0ZEE4
-
-
4.1.2.13 Vibrio campbellii A7MTQ6
-
-
4.1.2.13 Vibrio campbellii ATCC BAA-1116 A7MTQ6
-
-
4.1.2.13 Vibrio harveyi
-
-
-
4.1.2.13 Vibrio harveyi ATCC BAA-1116
-
-
-

Purification (Commentary)

EC Number Purification (Comment) Organism
4.1.2.13
-
 Edwardsiella tarda
4.1.2.13
-
 Vibrio anguillarum
4.1.2.13
-
 Aeromonas hydrophila
4.1.2.13
-
 Vibrio campbellii
4.1.2.13
-
 Vibrio alginolyticus
4.1.2.13 Ni-NTA column chromatography Vibrio harveyi
4.1.2.13 Ni-NTA column chromatography Aeromonas hydrophila
4.1.2.13 Ni-NTA column chromatography Vibrio alginolyticus
4.1.2.13 Ni-NTA column chromatography Vibrio anguillarum
4.1.2.13 Ni-NTA column chromatography Edwardsiella tarda

Substrates and Products (Substrate)

EC Number Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
4.1.2.13 D-fructose 1,6-bisphosphate
-
 Vibrio harveyi glycerone phosphate + D-glyceraldehyde 3-phosphate
-
 ?
4.1.2.13 D-fructose 1,6-bisphosphate
-
 Aeromonas hydrophila glycerone phosphate + D-glyceraldehyde 3-phosphate
-
 ?
4.1.2.13 D-fructose 1,6-bisphosphate
-
 Vibrio alginolyticus glycerone phosphate + D-glyceraldehyde 3-phosphate
-
 ?
4.1.2.13 D-fructose 1,6-bisphosphate
-
 Vibrio anguillarum glycerone phosphate + D-glyceraldehyde 3-phosphate
-
 ?
4.1.2.13 D-fructose 1,6-bisphosphate
-
 Edwardsiella tarda glycerone phosphate + D-glyceraldehyde 3-phosphate
-
 ?
4.1.2.13 D-fructose 1,6-bisphosphate
-
 Vibrio harveyi ATCC BAA-1116 glycerone phosphate + D-glyceraldehyde 3-phosphate
-
 ?
4.1.2.13 D-fructose 1,6-bisphosphate
-
 Vibrio anguillarum MVM425 glycerone phosphate + D-glyceraldehyde 3-phosphate
-
 ?
4.1.2.13 D-fructose 1,6-bisphosphate
-
 Edwardsiella tarda EIB202 glycerone phosphate + D-glyceraldehyde 3-phosphate
-
 ?
4.1.2.13 D-fructose 1,6-bisphosphate
-
 Vibrio alginolyticus 12G01 glycerone phosphate + D-glyceraldehyde 3-phosphate
-
 ?
4.1.2.13 D-fructose 1,6-bisphosphate
-
 Aeromonas hydrophila ATCC7699 glycerone phosphate + D-glyceraldehyde 3-phosphate
-
 ?

Synonyms

EC Number Synonyms Comment Organism
4.1.2.13 FBA
-
 Vibrio harveyi
4.1.2.13 FBA
-
 Aeromonas hydrophila
4.1.2.13 FBA
-
 Vibrio alginolyticus
4.1.2.13 FBA
-
 Vibrio anguillarum
4.1.2.13 FBA
-
 Edwardsiella tarda
4.1.2.13 FBA
-
 Vibrio campbellii
4.1.2.13 Fructose 1,6-bisphosphate aldolase
-
 Vibrio harveyi
4.1.2.13 Fructose 1,6-bisphosphate aldolase
-
 Aeromonas hydrophila
4.1.2.13 Fructose 1,6-bisphosphate aldolase
-
 Vibrio alginolyticus
4.1.2.13 Fructose 1,6-bisphosphate aldolase
-
 Vibrio anguillarum
4.1.2.13 Fructose 1,6-bisphosphate aldolase
-
 Edwardsiella tarda
4.1.2.13 Fructose 1,6-bisphosphate aldolase
-
 Vibrio campbellii

General Information

EC Number General Information Comment Organism
4.1.2.13 evolution the fact that fructose 1,6-bisphosphate aldolase of prokaryotes has little homology with the fructose 1,6-bisphosphate aldolase of eukaryotes provides an advantage for vaccine development Edwardsiella tarda
4.1.2.13 evolution the fact that fructose 1,6-bisphosphate aldolase of prokaryotes has little homology with the fructose 1,6-bisphosphate aldolase of eukaryotes provides an advantage for vaccine development Vibrio anguillarum
4.1.2.13 evolution the fact that fructose 1,6-bisphosphate aldolase of prokaryotes has little homology with the fructose 1,6-bisphosphate aldolase of eukaryotes provides an advantage for vaccine development Aeromonas hydrophila
4.1.2.13 evolution the fact that fructose 1,6-bisphosphate aldolase of prokaryotes has little homology with the fructose 1,6-bisphosphate aldolase of eukaryotes provides an advantage for vaccine development Vibrio campbellii
4.1.2.13 evolution the fact that fructose 1,6-bisphosphate aldolase of prokaryotes has little homology with the fructose 1,6-bisphosphate aldolase of eukaryotes provides an advantage for vaccine development Vibrio alginolyticus
4.1.2.13 physiological function conserved enzyme in the glycolytic pathway. The enzyme also has protection efficacy Edwardsiella tarda
4.1.2.13 physiological function conserved enzyme in the glycolytic pathway. The enzyme also has protection efficacy Vibrio anguillarum
4.1.2.13 physiological function conserved enzyme in the glycolytic pathway. The enzyme also has protection efficacy Aeromonas hydrophila
4.1.2.13 physiological function conserved enzyme in the glycolytic pathway. The enzyme also has protection efficacy Vibrio campbellii
4.1.2.13 physiological function conserved enzyme in the glycolytic pathway. The enzyme also has protection efficacy Vibrio alginolyticus