EC Number | Activating Compound | Comment | Organism | Structure |
---|---|---|---|---|
5.3.99.3 | GSH | the enzyme activity is increased in the presence of reduced glutathione | Gammarus sp. KV-2010a | |
5.3.99.3 | GSH | the enzyme activity is increased in the presence of reduced glutathione | Caprella sp. KV-2010a |
EC Number | Cloned (Comment) | Organism |
---|---|---|
5.3.99.3 | expressed in Escherichia coli BL21(DE3)RP cells | Gammarus sp. KV-2010a |
5.3.99.3 | expressed in Escherichia coli BL21(DE3)RP cells | Caprella sp. KV-2010a |
EC Number | General Stability | Organism |
---|---|---|
5.3.99.3 | the enzyme stability is increased in the presence of reduced glutathione | Gammarus sp. KV-2010a |
5.3.99.3 | the enzyme stability is increased in the presence of reduced glutathione | Caprella sp. KV-2010a |
EC Number | Inhibitors | Comment | Organism | Structure |
---|---|---|---|---|
5.3.99.3 | 4-hydroxymercuribenzoate | - |
Caprella sp. KV-2010a | |
5.3.99.3 | 4-hydroxymercuribenzoate | - |
Gammarus sp. KV-2010a |
EC Number | Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|---|
5.3.99.3 | membrane | - |
Gammarus sp. KV-2010a | 16020 | - |
5.3.99.3 | membrane | - |
Caprella sp. KV-2010a | 16020 | - |
EC Number | Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|---|
5.3.99.3 | Prostaglandin H2 | Gammarus sp. KV-2010a | - |
Prostaglandin E2 | - |
? | |
5.3.99.3 | Prostaglandin H2 | Caprella sp. KV-2010a | - |
Prostaglandin E2 | - |
? |
EC Number | Organism | UniProt | Comment | Textmining |
---|---|---|---|---|
5.3.99.3 | Caprella sp. KV-2010a | S4VIU3 | - |
- |
5.3.99.3 | Gammarus sp. KV-2010a | S4VLK7 | - |
- |
EC Number | Purification (Comment) | Organism |
---|---|---|
5.3.99.3 | Ni-NTA column chromatography, and Superdex 200 gel filtration | Gammarus sp. KV-2010a |
5.3.99.3 | Ni-NTA column chromatography, and Superdex 200 gel filtration | Caprella sp. KV-2010a |
EC Number | Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|---|
5.3.99.3 | Prostaglandin H2 | - |
Gammarus sp. KV-2010a | Prostaglandin E2 | - |
? | |
5.3.99.3 | Prostaglandin H2 | - |
Caprella sp. KV-2010a | Prostaglandin E2 | - |
? |
EC Number | Subunits | Comment | Organism |
---|---|---|---|
5.3.99.3 | ? | x * 39000, N-terminally truncated His6-tagged enzyme, SDS-PAGE | Gammarus sp. KV-2010a |
5.3.99.3 | ? | x * 39000, N-terminally truncated His6-tagged enzyme, SDS-PAGE | Caprella sp. KV-2010a |
EC Number | Synonyms | Comment | Organism |
---|---|---|---|
5.3.99.3 | PGE synthase | - |
Gammarus sp. KV-2010a |
5.3.99.3 | PGE synthase | - |
Caprella sp. KV-2010a |
5.3.99.3 | PGES-2 | - |
Gammarus sp. KV-2010a |
5.3.99.3 | PGES-2 | - |
Caprella sp. KV-2010a |
5.3.99.3 | prostaglandin E synthase-2 | - |
Gammarus sp. KV-2010a |
5.3.99.3 | prostaglandin E synthase-2 | - |
Caprella sp. KV-2010a |