BRENDA - Enzyme Database show

Lipocalin-type prostaglandin D2 synthase reduces glucagon secretion in alpha TC-1 clone 6 cells via the DP1 receptor

Davani, D.; Kumar, S.; Palaia, T.; Hall, C.; Ragolia, L.; Biochem. Biophys. Rep. 4, 224-227 (2015)

Data extracted from this reference:

Natural Substrates/ Products (Substrates)
EC Number
Natural Substrates
Organism
Commentary (Nat. Sub.)
Natural Products
Commentary (Nat. Pro.)
Organism (Nat. Pro.)
Reversibility
5.3.99.2
Prostaglandin H2
Mus musculus
-
Prostaglandin D2
-
-
?
Organism
EC Number
Organism
Primary Accession No. (UniProt)
Commentary
Textmining
5.3.99.2
Mus musculus
O09114
-
-
Source Tissue
EC Number
Source Tissue
Commentary
Organism
Textmining
5.3.99.2
alpha-TC1.6 cell
-
Mus musculus
-
5.3.99.2
pancreatic islet
-
Mus musculus
-
Substrates and Products (Substrate)
EC Number
Substrates
Commentary Substrates
Literature (Substrates)
Organism
Products
Commentary (Products)
Literature (Products)
Organism (Products)
Reversibility
5.3.99.2
Prostaglandin H2
-
746950
Mus musculus
Prostaglandin D2
-
-
-
?
Natural Substrates/ Products (Substrates) (protein specific)
EC Number
Natural Substrates
Organism
Commentary (Nat. Sub.)
Natural Products
Commentary (Nat. Pro.)
Organism (Nat. Pro.)
Reversibility
5.3.99.2
Prostaglandin H2
Mus musculus
-
Prostaglandin D2
-
-
?
Source Tissue (protein specific)
EC Number
Source Tissue
Commentary
Organism
Textmining
5.3.99.2
alpha-TC1.6 cell
-
Mus musculus
-
5.3.99.2
pancreatic islet
-
Mus musculus
-
Substrates and Products (Substrate) (protein specific)
EC Number
Substrates
Commentary Substrates
Literature (Substrates)
Organism
Products
Commentary (Products)
Literature (Products)
Organism (Products)
Reversibility
5.3.99.2
Prostaglandin H2
-
746950
Mus musculus
Prostaglandin D2
-
-
-
?
General Information
EC Number
General Information
Commentary
Organism
5.3.99.2
physiological function
higher enzyme concentrations significantly reduce the secretion of glucagon in alpha cells, which may contribute to the pathogenesis of diabetes
Mus musculus
General Information (protein specific)
EC Number
General Information
Commentary
Organism
5.3.99.2
physiological function
higher enzyme concentrations significantly reduce the secretion of glucagon in alpha cells, which may contribute to the pathogenesis of diabetes
Mus musculus